Non small-cell lung cancer with metastasis to thigh muscle and mandible: Two case reports

Francesca Maria Giugliano, Domingo Alberti, Giovanna Guida, Giampaolo De Palma, Luciano Iadanza, Maria Mormile, Fabrizio Cammarota, Agnese Montanino, Franco Fulciniti, Vincenzo Ravo, Paolo Muto

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Introduction. Lung cancer is the leading cause of cancer-related death in Europe and the US. Isolated metastases to skeletal muscle and the mandible are very uncommon. Case presentation. This report presents two cases. Case 1 concerns a 45-year-old Caucasian woman affected by muscle metastasis of the right thigh from non-small-cell lung cancer. Case 2 concerns a 61-year-old Caucasian man affected by mandible metastasis from non-small-cell lung cancer. Both metastases were detected by diagnostic imaging studies. Both patients were treated with radiation therapy with palliative and antalgic intent. Conclusion: Radiation therapy was effective and well tolerated in both cases. Both our patients are alive, with follow-up of 18 months and five months, respectively.

Original languageEnglish
Article number98
JournalJournal of Medical Case Reports
Publication statusPublished - 2013


  • Bone mandible metastasis
  • Muscle metastasis
  • Non-small-cell lung cancer
  • Radiation therapy

ASJC Scopus subject areas

  • Medicine(all)


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