Non-telomeric chromosome localization of (TTAGGG)(n) repeats in the genus Eulemur

Silvia Garagna, Elena Ronchetti, Silvia Mascheretti, Sergio Crovella, Daniele Formenti, Yves Rumpler, Maria G Manfredi Romanini

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Abstract

The chromosomal distribution of the (TTAGGG)(n) telomeric repetitive sequences was studied in the Malagasy species Eulemur fulvus fulvus (2n = 60), Eulemur rubriventer (2n = 50), Eulemur coronatus (2n = 46) and Eulemur macaco (2n = 44). These sequences hybridize to the telomeres of all chromosomes of the four species and also to the pericentromeres of all chromosomes of E. fulvus, E. coronatus and E. macaco, with the exception of the pericentromeres of E. coronatus and E. macaco chromosomes 9, the homeologous E. fulvus chromosomes 2 and E. macaco chromosomes 1. In E. rubriventer only a very weak signal was detected at the pericentromeres of a few chromosomes. In E. fulvus, E. coronatus and E. macaco, non-telomeric (TTAGGG)(n) sequences collocalize with constitutive heterochromatin. The interspecific differences of the hybridization pattern of (TTAGGG)(n) sequences at the pericentromeres suggest that E. rubriventer branched off the common trunk before amplification of endogenous (TTAGGG)(n) sequences occurred in pericentromeric regions.

Original languageEnglish
Pages (from-to)487-491
Number of pages5
JournalChromosome Research
Volume5
Issue number7
Publication statusPublished - 1997

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Keywords

  • Eulemur
  • Heterochromatin
  • Telomeric sequence

ASJC Scopus subject areas

  • Genetics

Cite this

Garagna, S., Ronchetti, E., Mascheretti, S., Crovella, S., Formenti, D., Rumpler, Y., & Romanini, M. G. M. (1997). Non-telomeric chromosome localization of (TTAGGG)(n) repeats in the genus Eulemur. Chromosome Research, 5(7), 487-491.