Abstract
Fractional photothermolysis has been shown to improve various types of scarring, including atrophic acne scars. The aim of the present authors was to assess the efficacy and safety of the nonablative fractional photothermolysis in the treatment of moderate and severe acne scars. Eighty-seven patients with moderate or severe acne scarring were treated with six sessions with a 1540-nm Erbium glass fiber laser at 3-week intervals. Six months after the final session, 7/87 (8%) patients showed a moderate improvement, whereas 80/87 (92%) patients had a marked improvement. In a subset of patients, the present authors also applied in vivo reflectance confocal microscopy to highlight the relevant microscopic changes. Hence, early and late posttreatment findings, most importantly the replacement of a coarser collagen with a new one, similar to the collagen seen in healthy skin, were observed. In accordance to previous studies, the present authors conclude that nonablative fractional photothermolysis is a safe and effective treatment for moderate or severe acne scarring.
| Original language | English |
|---|---|
| Pages (from-to) | 463-467 |
| Number of pages | 5 |
| Journal | Dermatologic Therapy |
| Volume | 25 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - Sep 2012 |
Fingerprint
Keywords
- acne scarring
- fractional photothermolysis
- in vivo confocal microscopy
- nonablative fractional lasers
ASJC Scopus subject areas
- Dermatology
Cite this
Nonablative fractional photothermolysis for acne scars : Clinical and in vivo microscopic documentation of treatment efficacy. / Bencini, Pier Luca; Tourlaki, Athanasia; Galimberti, Michela; Longo, Caterina; Pellacani, Giovanni; De Giorgi, Vincenzo; Guerriero, Giuseppe.
In: Dermatologic Therapy, Vol. 25, No. 5, 09.2012, p. 463-467.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Nonablative fractional photothermolysis for acne scars
T2 - Clinical and in vivo microscopic documentation of treatment efficacy
AU - Bencini, Pier Luca
AU - Tourlaki, Athanasia
AU - Galimberti, Michela
AU - Longo, Caterina
AU - Pellacani, Giovanni
AU - De Giorgi, Vincenzo
AU - Guerriero, Giuseppe
PY - 2012/9
Y1 - 2012/9
N2 - Fractional photothermolysis has been shown to improve various types of scarring, including atrophic acne scars. The aim of the present authors was to assess the efficacy and safety of the nonablative fractional photothermolysis in the treatment of moderate and severe acne scars. Eighty-seven patients with moderate or severe acne scarring were treated with six sessions with a 1540-nm Erbium glass fiber laser at 3-week intervals. Six months after the final session, 7/87 (8%) patients showed a moderate improvement, whereas 80/87 (92%) patients had a marked improvement. In a subset of patients, the present authors also applied in vivo reflectance confocal microscopy to highlight the relevant microscopic changes. Hence, early and late posttreatment findings, most importantly the replacement of a coarser collagen with a new one, similar to the collagen seen in healthy skin, were observed. In accordance to previous studies, the present authors conclude that nonablative fractional photothermolysis is a safe and effective treatment for moderate or severe acne scarring.
AB - Fractional photothermolysis has been shown to improve various types of scarring, including atrophic acne scars. The aim of the present authors was to assess the efficacy and safety of the nonablative fractional photothermolysis in the treatment of moderate and severe acne scars. Eighty-seven patients with moderate or severe acne scarring were treated with six sessions with a 1540-nm Erbium glass fiber laser at 3-week intervals. Six months after the final session, 7/87 (8%) patients showed a moderate improvement, whereas 80/87 (92%) patients had a marked improvement. In a subset of patients, the present authors also applied in vivo reflectance confocal microscopy to highlight the relevant microscopic changes. Hence, early and late posttreatment findings, most importantly the replacement of a coarser collagen with a new one, similar to the collagen seen in healthy skin, were observed. In accordance to previous studies, the present authors conclude that nonablative fractional photothermolysis is a safe and effective treatment for moderate or severe acne scarring.
KW - acne scarring
KW - fractional photothermolysis
KW - in vivo confocal microscopy
KW - nonablative fractional lasers
UR - http://www.scopus.com/inward/record.url?scp=84867383730&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84867383730&partnerID=8YFLogxK
U2 - 10.1111/j.1529-8019.2012.01478.x
DO - 10.1111/j.1529-8019.2012.01478.x
M3 - Article
C2 - 23046026
AN - SCOPUS:84867383730
VL - 25
SP - 463
EP - 467
JO - Dermatologic Therapy
JF - Dermatologic Therapy
SN - 1396-0296
IS - 5
ER -