Noncoding RNA interplay with the Genome

Research output: Contribution to journalArticlepeer-review

Abstract

The majority of our genome is transcribed to produce RNA molecules that are mostly noncoding. Among them, long noncoding RNAs (lncRNAs) are the most numerous and functionally versatile class. LncRNAs have emerged as key regulators of gene expression at multiple levels. This section describes bioinformatics aspects important for lncRNA discovery and molecular approaches to perform structure-function characterization of this exciting class of regulatory molecules.

Original languageEnglish
Pages (from-to)69-72
Number of pages4
JournalMethods in Molecular Biology
Volume1480
DOIs
Publication statusPublished - 2016

Keywords

  • Bioinformatics
  • Chart
  • ChIRP
  • LncRNA
  • RAP
  • RIP
  • RNA pull-down
  • RNA-seq

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

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