Noncoding RNA interplay with the Genome

Davide Gabellini

doi:10.1007/978-1-4939-6380-5_6

Noncoding RNA interplay with the Genome

Davide Gabellini

IRCCS Ospedale San Raffaele

Research output: Contribution to journal › Article › peer-review

Abstract

The majority of our genome is transcribed to produce RNA molecules that are mostly noncoding. Among them, long noncoding RNAs (lncRNAs) are the most numerous and functionally versatile class. LncRNAs have emerged as key regulators of gene expression at multiple levels. This section describes bioinformatics aspects important for lncRNA discovery and molecular approaches to perform structure-function characterization of this exciting class of regulatory molecules.

Original language	English
Pages (from-to)	69-72
Number of pages	4
Journal	Methods in Molecular Biology
Volume	1480
DOIs	https://doi.org/10.1007/978-1-4939-6380-5_6
Publication status	Published - 2016

Keywords

Bioinformatics
Chart
ChIRP
LncRNA
RAP
RIP
RNA pull-down
RNA-seq

ASJC Scopus subject areas

Molecular Biology
Genetics

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10.1007/978-1-4939-6380-5_6

Cite this

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abstract = "The majority of our genome is transcribed to produce RNA molecules that are mostly noncoding. Among them, long noncoding RNAs (lncRNAs) are the most numerous and functionally versatile class. LncRNAs have emerged as key regulators of gene expression at multiple levels. This section describes bioinformatics aspects important for lncRNA discovery and molecular approaches to perform structure-function characterization of this exciting class of regulatory molecules.",

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AB - The majority of our genome is transcribed to produce RNA molecules that are mostly noncoding. Among them, long noncoding RNAs (lncRNAs) are the most numerous and functionally versatile class. LncRNAs have emerged as key regulators of gene expression at multiple levels. This section describes bioinformatics aspects important for lncRNA discovery and molecular approaches to perform structure-function characterization of this exciting class of regulatory molecules.

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KW - RAP

KW - RIP

KW - RNA pull-down

KW - RNA-seq

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Noncoding RNA interplay with the Genome

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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