Abstract
The majority of our genome is transcribed to produce RNA molecules that are mostly noncoding. Among them, long noncoding RNAs (lncRNAs) are the most numerous and functionally versatile class. LncRNAs have emerged as key regulators of gene expression at multiple levels. This section describes bioinformatics aspects important for lncRNA discovery and molecular approaches to perform structure-function characterization of this exciting class of regulatory molecules.
Original language | English |
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Pages (from-to) | 69-72 |
Number of pages | 4 |
Journal | Methods in Molecular Biology |
Volume | 1480 |
DOIs | |
Publication status | Published - 2016 |
Keywords
- Bioinformatics
- Chart
- ChIRP
- LncRNA
- RAP
- RIP
- RNA pull-down
- RNA-seq
ASJC Scopus subject areas
- Molecular Biology
- Genetics