Noncoding RNAs: Emerging players in muscular dystrophies

Germana Falcone, Alessandra Perfetti, Beatrice Cardinali, Fabio Martelli

Research output: Contribution to journalArticle

Abstract

The fascinating world of noncoding RNAs has recently come to light, thanks to the development of powerful sequencing technologies, revealing a variety of RNA molecules playing important regulatory functions in most, if not all, cellular processes. Many noncoding RNAs have been implicated in regulatory networks that are determinant for skeletal muscle differentiation and disease. In this review, we outline the noncoding RNAs involved in physiological mechanisms of myogenesis and those that appear dysregulated in muscle dystrophies, also discussing their potential use as disease biomarkers and therapeutic targets.

Original languageEnglish
Article number503634
JournalBioMed Research International
Volume2014
DOIs
Publication statusPublished - 2014

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)
  • Medicine(all)

Fingerprint Dive into the research topics of 'Noncoding RNAs: Emerging players in muscular dystrophies'. Together they form a unique fingerprint.

  • Cite this