Noninvasive assessment of baroreflex sensitivity in post-MI patients by an open loop parametric model of RR-systolic pressure interactions

Luca Faes, Giandomenico Nollo, Alberto Porta, Flavia Ravelli

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Noninvasive evaluation of baroreflex sensitivity is considered an important goal for diagnosis and prognosis in post-MI patients. Methodological approach and physiological measure conditions may be the main causes for the differences found with respect to the standard Phenylephrine test. In this study, three linear parametric models, describing variability and mutual interactions of RR interval and systolic arterial pressure (SAP), were compared in relation to their ability to quantify baroreflex gain, using the Phenylephrine test index (PheBRS) as reference. By monovariate autoregressive (AR) model, bivariate AR model and open loop ARXAR model, specific gain indexes (αAR, α2AR, αARXAR) were calculated. Variance and regression analysis selected αARXAR first in correlation with PheBRS, demonstrating that a better agreement is achieved using the ARXAR model, specifically designed to describe the causal influences of SAP on RR interval.

Original languageEnglish
Title of host publicationComputers in Cardiology
PublisherIEEE
Pages217-220
Number of pages4
Publication statusPublished - 1999
EventThe 26th Annual Meeting: Computers in Cardiology 1999 - Hannover, Ger
Duration: Sep 26 1999Sep 29 1999

Other

OtherThe 26th Annual Meeting: Computers in Cardiology 1999
CityHannover, Ger
Period9/26/999/29/99

ASJC Scopus subject areas

  • Software
  • Cardiology and Cardiovascular Medicine

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