TY - JOUR
T1 - Noninvasive assessment of coronary anatomy and myocardial perfusion
T2 - Going toward an integrated imaging approach
AU - Petretta, Mario
AU - Costanzo, Pierluigi
AU - Acampa, Wanda
AU - Imbriaco, Massimo
AU - Ferro, Adele
AU - Filardi, Pasquale Perrone
AU - Cuocolo, Alberto
PY - 2008/10
Y1 - 2008/10
N2 - Many noninvasive imaging techniques are available for the evaluation of patients with known or suspected chronic coronary artery disease. Among these, computed tomography-based techniques allow the quantification of coronary atherosclerotic calcium and noninvasive imaging of coronary arteries, whereas nuclear cardiology is the most widely used noninvasive approach for the assessment of myocardial perfusion. The available single-photon emission computed tomography flow agents are characterized by a cardiac uptake proportional to myocardial blood flow. In addition, different positron emission tomography tracers may be used for the quantitative measurement of myocardial blood flow and coronary flow reserve. Extensive research is currently being performed in the development of noninvasive coronary angiography and myocardial perfusion imaging using cardiac magnetic resonance. Finally, new multimodality imaging systems have been recently developed, bringing together anatomical and functional information. This review sought to provide a description of the relative merits of noninvasive imaging techniques in the assessment of coronary anatomy and myocardial perfusion in patients with known or suspected coronary artery disease.
AB - Many noninvasive imaging techniques are available for the evaluation of patients with known or suspected chronic coronary artery disease. Among these, computed tomography-based techniques allow the quantification of coronary atherosclerotic calcium and noninvasive imaging of coronary arteries, whereas nuclear cardiology is the most widely used noninvasive approach for the assessment of myocardial perfusion. The available single-photon emission computed tomography flow agents are characterized by a cardiac uptake proportional to myocardial blood flow. In addition, different positron emission tomography tracers may be used for the quantitative measurement of myocardial blood flow and coronary flow reserve. Extensive research is currently being performed in the development of noninvasive coronary angiography and myocardial perfusion imaging using cardiac magnetic resonance. Finally, new multimodality imaging systems have been recently developed, bringing together anatomical and functional information. This review sought to provide a description of the relative merits of noninvasive imaging techniques in the assessment of coronary anatomy and myocardial perfusion in patients with known or suspected coronary artery disease.
KW - Coronary anatomy
KW - Coronary artery disease
KW - Myocardial perfusion
KW - Noninvasive imaging
UR - http://www.scopus.com/inward/record.url?scp=55249103675&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=55249103675&partnerID=8YFLogxK
U2 - 10.2459/JCM.0b013e328306f311
DO - 10.2459/JCM.0b013e328306f311
M3 - Article
C2 - 18799959
AN - SCOPUS:55249103675
VL - 9
SP - 977
EP - 986
JO - Journal of Cardiovascular Medicine
JF - Journal of Cardiovascular Medicine
SN - 1558-2027
IS - 10
ER -