Lesioni mammarie non palpabili: la guida radiologica preoperatoria nella ROLL (radioguided occult lesion localisation)

Translated title of the contribution: Nonpalpable breast lesions: Preoperative radiological guidance in radioguided occult lesion localisation (ROLL)

E. Belloni, C. Canevari, P. Panizza, A. Marassi, M. Rodighiero, S. Tacchini, V. Zuber, I. Sassi, L. Gianolli, F. Fazio, A. Del Maschio

Research output: Contribution to journalArticle

Abstract

Purpose: This study evaluated the methods, technical aspects and impact of preoperative radiological guidance in radioguided occult lesion localisation (ROLL) for single nonpalpable breast lesions. Materials and methods: A total of 288 patients underwent ROLL before surgery. Human serum albumin macroaggregates labelled with 3.7-7.4 MBq of technetium99 were injected into the lesion. In the case of ultrasonographic guidance (221/288 patients), inoculum positioning resulted in a change of echogenicity at the lesion site. In the case of mammographic guidance (67/288 patients), iodinated contrast medium was injected following the radiotracer for subsequent mammographic evaluation. Patients underwent surgery within 24 h from ROLL. A gamma-detecting probe was used to locate the lesion during surgery and guide its removal. After excision, the specimen was examined by either ultrasonography or mammography to verify complete lesion removal before histological evaluation. Results: The lesion was correctly localised in 281/288 patients (97.5%). One ROLL procedure failed because surgery could not be performed within 24 h and the radioactivity decayed. Of the six incorrect localisations, 2 were due to the radiological guidance and 4 to technetium99 dispersion. Conclusions: Radiological guidance in ROLL ensured the outcome of the procedure of localisation and removal of single, nonpalpable breast lesions in the majority of cases.

Translated title of the contributionNonpalpable breast lesions: Preoperative radiological guidance in radioguided occult lesion localisation (ROLL)
Original languageItalian
Pages (from-to)564-574
Number of pages11
JournalRadiologia Medica
Volume116
Issue number4
DOIs
Publication statusPublished - Jun 2011

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Medicine(all)

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