Nonsecretory multiple myeloma: Presenting findings, clinical course and prognosis1

Michele Cavo, Piero Galieni, Marco Gobbi, Luca Baldrati, Loretta Leardini, Michele Baccarani, Sante Tura

Research output: Contribution to journalArticlepeer-review


The present report gives information both on the clinical features at presentation and the clinical course of 7 consecutive patients with nonsecretory multiple myeloma. It provides evidence that the nonsecretory variant was closely associated with high tumor cell mass, as determined by severe anemia and/or multiple areas of bone destruction. The marked depression of normal immunoglobulins and the absence of both renal failure and hypercalcemia differentiated nonsecretory from typical myelomatosis. Finally, the survival length of patients with nonsecretory myeloma appeared to be similar to that of comparably staged patients with secretory myeloma.

Original languageEnglish
Pages (from-to)27-30
Number of pages4
JournalActa Haematologica
Issue number1
Publication statusPublished - 1985


  • Myeloma, nonsecretory

ASJC Scopus subject areas

  • Hematology


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