Nonuniform strut distribution correlates with more neointimal hyperplasia after sirolimus-eluting stent implantation

Hideo Takebayashi, Gary S. Mintz, Stéphane G. Carlier, Yoshio Kobayashi, Kenichi Fujii, Takenori Yasuda, Ricardo A. Costa, Issam Moussa, George D. Dangas, Roxana Mehran, Alexandra J. Lansky, Edward Kreps, Michael B. Collins, Antonio Colombo, Gregg W. Stone, Martin B. Leon, Jeffrey W. Moses

Research output: Contribution to journalArticle

Abstract

Background - Little is known about causes of intimal hyperplasia (IH) after sirolimus-eluting stent (SES) implantation. Methods and Results - Intravascular ultrasound was performed in 24 lesions with intra-SES restenosis and a comparison group of 25 nonrestenotic SESs. To assess stent strut distribution, the maximum interstrut angle was measured with a protractor centered on the stent, and the visible struts were counted and normalized for the number of stent cells. In SES restenosis patients, minimum lumen site was compared with image slices 2.5, 5.0, 7.5, and 10.0 mm proximal and distal to this site. The minimum lumen site had a smaller IVUS lumen area at follow-up (2.7±0.9 versus 6.2±1.9 mm2; P2; P

Original languageEnglish
Pages (from-to)3430-3434
Number of pages5
JournalCirculation
Volume110
Issue number22
DOIs
Publication statusPublished - Nov 30 2004

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Keywords

  • Restenosis
  • Stents
  • Ultrasonics

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine

Cite this

Takebayashi, H., Mintz, G. S., Carlier, S. G., Kobayashi, Y., Fujii, K., Yasuda, T., Costa, R. A., Moussa, I., Dangas, G. D., Mehran, R., Lansky, A. J., Kreps, E., Collins, M. B., Colombo, A., Stone, G. W., Leon, M. B., & Moses, J. W. (2004). Nonuniform strut distribution correlates with more neointimal hyperplasia after sirolimus-eluting stent implantation. Circulation, 110(22), 3430-3434. https://doi.org/10.1161/01.CIR.0000148371.53174.05