Nonuniform strut distribution correlates with more neointimal hyperplasia after sirolimus-eluting stent implantation

Hideo Takebayashi; Gary S. Mintz; Stéphane G. Carlier; Yoshio Kobayashi; Kenichi Fujii; Takenori Yasuda; Ricardo A. Costa; Issam Moussa; George D. Dangas; Roxana Mehran; Alexandra J. Lansky; Edward Kreps; Michael B. Collins; Antonio Colombo; Gregg W. Stone; Martin B. Leon; Jeffrey W. Moses

doi:10.1161/01.CIR.0000148371.53174.05

Nonuniform strut distribution correlates with more neointimal hyperplasia after sirolimus-eluting stent implantation

Hideo Takebayashi, Gary S. Mintz, Stéphane G. Carlier, Yoshio Kobayashi, Kenichi Fujii, Takenori Yasuda, Ricardo A. Costa, Issam Moussa, George D. Dangas, Roxana Mehran, Alexandra J. Lansky, Edward Kreps, Michael B. Collins, Antonio Colombo, Gregg W. Stone, Martin B. Leon, Jeffrey W. Moses

IRCCS Ospedale San Raffaele

Research output: Contribution to journal › Article

Abstract

Background - Little is known about causes of intimal hyperplasia (IH) after sirolimus-eluting stent (SES) implantation. Methods and Results - Intravascular ultrasound was performed in 24 lesions with intra-SES restenosis and a comparison group of 25 nonrestenotic SESs. To assess stent strut distribution, the maximum interstrut angle was measured with a protractor centered on the stent, and the visible struts were counted and normalized for the number of stent cells. In SES restenosis patients, minimum lumen site was compared with image slices 2.5, 5.0, 7.5, and 10.0 mm proximal and distal to this site. The minimum lumen site had a smaller IVUS lumen area at follow-up (2.7±0.9 versus 6.2±1.9 mm²; P2; P

Original language	English
Pages (from-to)	3430-3434
Number of pages	5
Journal	Circulation
Volume	110
Issue number	22
DOIs	https://doi.org/10.1161/01.CIR.0000148371.53174.05
Publication status	Published - Nov 30 2004

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Keywords

Restenosis
Stents
Ultrasonics

ASJC Scopus subject areas

Physiology
Cardiology and Cardiovascular Medicine

Cite this

Takebayashi, H., Mintz, G. S., Carlier, S. G., Kobayashi, Y., Fujii, K., Yasuda, T., Costa, R. A., Moussa, I., Dangas, G. D., Mehran, R., Lansky, A. J., Kreps, E., Collins, M. B., Colombo, A., Stone, G. W., Leon, M. B., & Moses, J. W. (2004). Nonuniform strut distribution correlates with more neointimal hyperplasia after sirolimus-eluting stent implantation. Circulation, 110(22), 3430-3434. https://doi.org/10.1161/01.CIR.0000148371.53174.05

Nonuniform strut distribution correlates with more neointimal hyperplasia after sirolimus-eluting stent implantation. / Takebayashi, Hideo; Mintz, Gary S.; Carlier, Stéphane G.; Kobayashi, Yoshio; Fujii, Kenichi; Yasuda, Takenori; Costa, Ricardo A.; Moussa, Issam; Dangas, George D.; Mehran, Roxana; Lansky, Alexandra J.; Kreps, Edward; Collins, Michael B.; Colombo, Antonio; Stone, Gregg W.; Leon, Martin B.; Moses, Jeffrey W.

In: Circulation, Vol. 110, No. 22, 30.11.2004, p. 3430-3434.

Research output: Contribution to journal › Article

Takebayashi, H, Mintz, GS, Carlier, SG, Kobayashi, Y, Fujii, K, Yasuda, T, Costa, RA, Moussa, I, Dangas, GD, Mehran, R, Lansky, AJ, Kreps, E, Collins, MB, Colombo, A, Stone, GW, Leon, MB & Moses, JW 2004, 'Nonuniform strut distribution correlates with more neointimal hyperplasia after sirolimus-eluting stent implantation', Circulation, vol. 110, no. 22, pp. 3430-3434. https://doi.org/10.1161/01.CIR.0000148371.53174.05

Takebayashi, Hideo ; Mintz, Gary S. ; Carlier, Stéphane G. ; Kobayashi, Yoshio ; Fujii, Kenichi ; Yasuda, Takenori ; Costa, Ricardo A. ; Moussa, Issam ; Dangas, George D. ; Mehran, Roxana ; Lansky, Alexandra J. ; Kreps, Edward ; Collins, Michael B. ; Colombo, Antonio ; Stone, Gregg W. ; Leon, Martin B. ; Moses, Jeffrey W. / Nonuniform strut distribution correlates with more neointimal hyperplasia after sirolimus-eluting stent implantation. In: Circulation. 2004 ; Vol. 110, No. 22. pp. 3430-3434.

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abstract = "Background - Little is known about causes of intimal hyperplasia (IH) after sirolimus-eluting stent (SES) implantation. Methods and Results - Intravascular ultrasound was performed in 24 lesions with intra-SES restenosis and a comparison group of 25 nonrestenotic SESs. To assess stent strut distribution, the maximum interstrut angle was measured with a protractor centered on the stent, and the visible struts were counted and normalized for the number of stent cells. In SES restenosis patients, minimum lumen site was compared with image slices 2.5, 5.0, 7.5, and 10.0 mm proximal and distal to this site. The minimum lumen site had a smaller IVUS lumen area at follow-up (2.7±0.9 versus 6.2±1.9 mm2; P2; P",

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AU - Fujii, Kenichi

AU - Yasuda, Takenori

AU - Costa, Ricardo A.

AU - Moussa, Issam

AU - Dangas, George D.

AU - Mehran, Roxana

AU - Lansky, Alexandra J.

AU - Kreps, Edward

AU - Collins, Michael B.

AU - Colombo, Antonio

AU - Stone, Gregg W.

AU - Leon, Martin B.

AU - Moses, Jeffrey W.

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N2 - Background - Little is known about causes of intimal hyperplasia (IH) after sirolimus-eluting stent (SES) implantation. Methods and Results - Intravascular ultrasound was performed in 24 lesions with intra-SES restenosis and a comparison group of 25 nonrestenotic SESs. To assess stent strut distribution, the maximum interstrut angle was measured with a protractor centered on the stent, and the visible struts were counted and normalized for the number of stent cells. In SES restenosis patients, minimum lumen site was compared with image slices 2.5, 5.0, 7.5, and 10.0 mm proximal and distal to this site. The minimum lumen site had a smaller IVUS lumen area at follow-up (2.7±0.9 versus 6.2±1.9 mm2; P2; P

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10.1161/01.CIR.0000148371.53174.05