Nonvisible subthreshold micropulse diode laser (810 nm) treatment of central serous chorioretinopathy. A pilot study

Paolo Lanzetta, F. Furlan, L. Morgante, D. Veritti, F. Bandello

Research output: Contribution to journalArticlepeer-review


Purpose. To verify the efficacy of nonvisible micropulse diode laser irradiation in the treatment of central serous chorioretinopathy (CSC). Methods. Twenty-two patients with CSC for a total of 24 eyes with a disease duration longer than 3 months were included in a prospective study. Patients underwent Early Treatment Diabetic Retinopathy Study visual acuity (VA) examination, dilated ophthalmoscopy, fluorescein angiograppy, and optical coherence tomography before treatment and during follow-up. Treatment with a micropulse diode laser was given with a duty cycle of 15%. Multiple spots were placed over and adjacent to the area of retinaf pigment epithelium leak or decompensation. Results. Mean follow-up was 14 months (range 3-36 months). Powers used ranged from 1 to 2 W (mean 1.35 W). Mean number of spots was 275 (range 90-400). Fourteen eyes were treated once, nine eyes received two to three treatmonts, and one eye had five treatments during a follow-up of 3 years. Subretinal fluid was resolved or improved in'two third of cases 1 month after laser treatment, and in three-quarters at the end of follow-up. Mean retinal thickness was 328 μm, 197 μm, and 168, μm before, 1 month after irradiation, and at the end of follow-up, respectively. No evidence of RPE or retinal changes due to laser treatment weré discernible in most of the eyes. Median VA was 20/ 32 (range 20/100-20/20) before treatment and 20/25 (range 20/200-20/20) at the end-of the follow-up. Conclusions. Nonvisible micropulse diode laser may have efficacy in the treatment of CSC. A randomized study with larger series is needed.

Original languageEnglish
Pages (from-to)934-940
Number of pages7
JournalEuropean Journal of Ophthalmology
Issue number6
Publication statusPublished - 2008


  • Central serous chorioretinopathy
  • Nonvisible micropulse laser

ASJC Scopus subject areas

  • Ophthalmology


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