Noradrenergic receptor sensitivity in obsessive compulsive disorder: II. Cortisol response to acute clonidine administration

Francesca Brambilla; Laura Bellodi; Giampaolo Perna; Cinzia Arancio; Angelo Bertani; Giulia Perini; Christian Carraro; Franco Gava

doi:10.1016/S0165-1781(96)03009-0

Noradrenergic receptor sensitivity in obsessive compulsive disorder: II. Cortisol response to acute clonidine administration

Francesca Brambilla, Laura Bellodi, Giampaolo Perna, Cinzia Arancio, Angelo Bertani, Giulia Perini, Christian Carraro, Franco Gava

IRCCS Ospedale San Raffaele

Research output: Contribution to journal › Article › peer-review

Abstract

Sensitivity of pre-synaptic α-2- and post-synaptic α-1- and β-adrenoceptors was investigated in 15 patients with obsessive-compulsive disorder (OCD) and in 15 age- and sex-matched healthy controls, by measuring cortisol responses to saline administration and to inhibition by clonidine (clon), a noradrenergic receptor agonist. Basal values of cortisol and responses to administration of saline and of cion were the same in patients and controls.

Original language	English
Pages (from-to)	163-168
Number of pages	6
Journal	Psychiatry Research
Volume	69
Issue number	2-3
DOIs	https://doi.org/10.1016/S0165-1781(96)03009-0
Publication status	Published - Mar 24 1997

Keywords

Adrenoceptors
Clonidine
Cortisol
Obsessive-compulsive disorder

ASJC Scopus subject areas

Psychiatry and Mental health
Biological Psychiatry
Psychology(all)

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10.1016/S0165-1781(96)03009-0

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abstract = "Sensitivity of pre-synaptic α-2- and post-synaptic α-1- and β-adrenoceptors was investigated in 15 patients with obsessive-compulsive disorder (OCD) and in 15 age- and sex-matched healthy controls, by measuring cortisol responses to saline administration and to inhibition by clonidine (clon), a noradrenergic receptor agonist. Basal values of cortisol and responses to administration of saline and of cion were the same in patients and controls.",

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AU - Brambilla, Francesca

AU - Bellodi, Laura

AU - Perna, Giampaolo

AU - Arancio, Cinzia

AU - Bertani, Angelo

AU - Perini, Giulia

AU - Carraro, Christian

AU - Gava, Franco

PY - 1997/3/24

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N2 - Sensitivity of pre-synaptic α-2- and post-synaptic α-1- and β-adrenoceptors was investigated in 15 patients with obsessive-compulsive disorder (OCD) and in 15 age- and sex-matched healthy controls, by measuring cortisol responses to saline administration and to inhibition by clonidine (clon), a noradrenergic receptor agonist. Basal values of cortisol and responses to administration of saline and of cion were the same in patients and controls.

AB - Sensitivity of pre-synaptic α-2- and post-synaptic α-1- and β-adrenoceptors was investigated in 15 patients with obsessive-compulsive disorder (OCD) and in 15 age- and sex-matched healthy controls, by measuring cortisol responses to saline administration and to inhibition by clonidine (clon), a noradrenergic receptor agonist. Basal values of cortisol and responses to administration of saline and of cion were the same in patients and controls.

KW - Adrenoceptors

KW - Clonidine

KW - Cortisol

KW - Obsessive-compulsive disorder

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Noradrenergic receptor sensitivity in obsessive compulsive disorder: II. Cortisol response to acute clonidine administration

Abstract

Keywords

ASJC Scopus subject areas

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