Sensitivity of pre-synaptic α-2- and post-synaptic α-1- and β-adrenoceptors was investigated in 15 patients with obsessive-compulsive disorder (OCD) and in 15 age- and sex-matched healthy controls, by measuring cortisol responses to saline administration and to inhibition by clonidine (clon), a noradrenergic receptor agonist. Basal values of cortisol and responses to administration of saline and of cion were the same in patients and controls.
- Obsessive-compulsive disorder
ASJC Scopus subject areas
- Psychiatry and Mental health
- Biological Psychiatry