Abstract
The data presented support the existence of a neural connection between the gonads and the hypothalamus. The morphological substrate of this neural pathway is unknown. Concerning the functional significance of this neural connection it seems possible that it plays a role in the development of compensatory ovarian hypertrophy and supports the view that a non-hormonal, neural component is involved in the development of compensatory ovarian hypertrophy. The abovementioned data are in good accordance with the observations made on the adrenal gland. Since compensatory organ growth occurs after specific tissue loss in the adrenal cortex, ovary, testis, thyroid gland, kidney, liver and salivary gland one can speculate that the postulated neural connection and its role in the development of compensatory hypertrophy might be a more general phenomenon. On the other hand the fact that after unilateral orchidectomy in rabbit there is a decreased intraocular pressure in the eye opposite to the removed testis (20) and in patients with unilateral testicular lesion pathological changes such as keratoconjunctivitis sicca, reduced tear production, occur in the eye contralateral to the testis affected, it seems possible that afferent nerves arising from the gonads terminate not only in neuroendocrine structures. Further studies are required to prove morphologically the supposed neural pathway between the adrenal, the gonads and the hypothalamus, to investigate its other probable role in the endocrine function and to study whether similar neural mechanism is involved in the development of compensatory hypertrophy of the thyroid, kidney, liver and salivary gland.
| Original language | English |
|---|---|
| Pages (from-to) | 327-331 |
| Number of pages | 5 |
| Journal | Acta Europaea Fertilitatis |
| Volume | 8 |
| Issue number | 4 |
| Publication status | Published - 1977 |
Fingerprint
ASJC Scopus subject areas
- Obstetrics and Gynaecology
Cite this
Norepinephrinergic involvement in the neuronal mechanism regulating compensatory ovarian hypertrophy. / Gerendai, I.; Marchetti, B.; Maugeri, S.; Prato, A.; Scapagnini, U.; Halasz, B.
In: Acta Europaea Fertilitatis, Vol. 8, No. 4, 1977, p. 327-331.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Norepinephrinergic involvement in the neuronal mechanism regulating compensatory ovarian hypertrophy
AU - Gerendai, I.
AU - Marchetti, B.
AU - Maugeri, S.
AU - Prato, A.
AU - Scapagnini, U.
AU - Halasz, B.
PY - 1977
Y1 - 1977
N2 - The data presented support the existence of a neural connection between the gonads and the hypothalamus. The morphological substrate of this neural pathway is unknown. Concerning the functional significance of this neural connection it seems possible that it plays a role in the development of compensatory ovarian hypertrophy and supports the view that a non-hormonal, neural component is involved in the development of compensatory ovarian hypertrophy. The abovementioned data are in good accordance with the observations made on the adrenal gland. Since compensatory organ growth occurs after specific tissue loss in the adrenal cortex, ovary, testis, thyroid gland, kidney, liver and salivary gland one can speculate that the postulated neural connection and its role in the development of compensatory hypertrophy might be a more general phenomenon. On the other hand the fact that after unilateral orchidectomy in rabbit there is a decreased intraocular pressure in the eye opposite to the removed testis (20) and in patients with unilateral testicular lesion pathological changes such as keratoconjunctivitis sicca, reduced tear production, occur in the eye contralateral to the testis affected, it seems possible that afferent nerves arising from the gonads terminate not only in neuroendocrine structures. Further studies are required to prove morphologically the supposed neural pathway between the adrenal, the gonads and the hypothalamus, to investigate its other probable role in the endocrine function and to study whether similar neural mechanism is involved in the development of compensatory hypertrophy of the thyroid, kidney, liver and salivary gland.
AB - The data presented support the existence of a neural connection between the gonads and the hypothalamus. The morphological substrate of this neural pathway is unknown. Concerning the functional significance of this neural connection it seems possible that it plays a role in the development of compensatory ovarian hypertrophy and supports the view that a non-hormonal, neural component is involved in the development of compensatory ovarian hypertrophy. The abovementioned data are in good accordance with the observations made on the adrenal gland. Since compensatory organ growth occurs after specific tissue loss in the adrenal cortex, ovary, testis, thyroid gland, kidney, liver and salivary gland one can speculate that the postulated neural connection and its role in the development of compensatory hypertrophy might be a more general phenomenon. On the other hand the fact that after unilateral orchidectomy in rabbit there is a decreased intraocular pressure in the eye opposite to the removed testis (20) and in patients with unilateral testicular lesion pathological changes such as keratoconjunctivitis sicca, reduced tear production, occur in the eye contralateral to the testis affected, it seems possible that afferent nerves arising from the gonads terminate not only in neuroendocrine structures. Further studies are required to prove morphologically the supposed neural pathway between the adrenal, the gonads and the hypothalamus, to investigate its other probable role in the endocrine function and to study whether similar neural mechanism is involved in the development of compensatory hypertrophy of the thyroid, kidney, liver and salivary gland.
UR - http://www.scopus.com/inward/record.url?scp=0017603325&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0017603325&partnerID=8YFLogxK
M3 - Article
C2 - 610315
AN - SCOPUS:0017603325
VL - 8
SP - 327
EP - 331
JO - Acta Europaea Fertilitatis
JF - Acta Europaea Fertilitatis
SN - 0587-2421
IS - 4
ER -