Normal levels of soluble CD4 in sera from patients with juvenile chronic arthritis

I. Prigione, A. Buoncompagni, M. Cutolo, P. Facchetti, G. Morreale, V. Pistoia

Research output: Contribution to journalArticlepeer-review

Abstract

Sera from a group of patients with juvenile chronic arthritis (JCA) were tested for soluble CD4 (sCD4). In most cases normal levels of the molecule were detected independent of disease activity. Similar results were obtained when sera from a population of adult rheumatoid arthritis (RA) patients were analyzed. Immunophenotypic studies of circulating mononuclear cells from seven JCA patients with active disease showed that T cells did not express activation markers. Finally, preliminary experiments showed that sCD4 levels were high in the synovial fluids from 3 RA patients as compared with paired serum determinations.

Original languageEnglish
Pages (from-to)341-344
Number of pages4
JournalClinical and Experimental Rheumatology
Volume11
Issue number3
Publication statusPublished - 1993

ASJC Scopus subject areas

  • Immunology
  • Rheumatology

Fingerprint Dive into the research topics of 'Normal levels of soluble CD4 in sera from patients with juvenile chronic arthritis'. Together they form a unique fingerprint.

Cite this