Normalisation of CD4 counts in patients with HIV-1 infection and maximum virological suppression who are taking combination antiretroviral therapy: an observational cohort study

A. Mocroft, AN Phillips, J. Gatell, B. Ledergerber, M. Fisher, N. Clumeck, M. Losso, A. Lazzarin, G. Fatkenheuer, JD Lundgren

Research output: Contribution to journalArticle

183 Citations (Scopus)

Abstract

Background: Combination antiretroviral therapy (cART) has been shown to reduce mortality and morbidity in patients with HIV. As viral replication falls, the CD4 count increases, but whether the CD4 count returns to the level seen in HIV-negative people is unknown. We aimed to assess whether the CD4 count for patients with maximum virological suppression (viral load

Original languageEnglish
Pages (from-to)407-413
Number of pages7
JournalLancet
Volume370
Issue number9585
DOIs
Publication statusPublished - Aug 4 2007

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CD4 Lymphocyte Count
HIV Infections
Observational Studies
HIV-1
Cohort Studies
HIV
Viral Load
Therapeutics
Morbidity
Mortality

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Normalisation of CD4 counts in patients with HIV-1 infection and maximum virological suppression who are taking combination antiretroviral therapy : an observational cohort study. / Mocroft, A.; Phillips, AN; Gatell, J.; Ledergerber, B.; Fisher, M.; Clumeck, N.; Losso, M.; Lazzarin, A.; Fatkenheuer, G.; Lundgren, JD.

In: Lancet, Vol. 370, No. 9585, 04.08.2007, p. 407-413.

Research output: Contribution to journalArticle

Mocroft, A, Phillips, AN, Gatell, J, Ledergerber, B, Fisher, M, Clumeck, N, Losso, M, Lazzarin, A, Fatkenheuer, G & Lundgren, JD 2007, 'Normalisation of CD4 counts in patients with HIV-1 infection and maximum virological suppression who are taking combination antiretroviral therapy: an observational cohort study', Lancet, vol. 370, no. 9585, pp. 407-413. https://doi.org/10.1016/S0140-6736(07)60948-9
Mocroft, A. ; Phillips, AN ; Gatell, J. ; Ledergerber, B. ; Fisher, M. ; Clumeck, N. ; Losso, M. ; Lazzarin, A. ; Fatkenheuer, G. ; Lundgren, JD. / Normalisation of CD4 counts in patients with HIV-1 infection and maximum virological suppression who are taking combination antiretroviral therapy : an observational cohort study. In: Lancet. 2007 ; Vol. 370, No. 9585. pp. 407-413.
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