Normative data for the Montreal Cognitive Assessment in an Italian population sample

Gabriella Santangelo, Mattia Siciliano, Roberto Pedone, Carmine Vitale, Fabrizia Falco, Rossella Bisogno, Pietro Siano, Paolo Barone, Dario Grossi, Franco Santangelo, Luigi Trojano

Research output: Contribution to journalArticle

Abstract

The Montreal Cognitive Assessment (MoCA) is a rapid screening battery, also including subtests to assess frontal functions such as set-shifting, abstraction and cognitive flexibility. MoCA seems to be useful to identify non-amnestic mild cognitive impairment (MCI) and subcortical dementia; it has high sensitivity and specificity in distinguishing MCI from mild Alzheimer’s Disease. Previous studies revealed that certain items of MoCA may be culturally biased and highlighted the need for population-based norms for the MoCA. The aim of present study was to collect normative values in a sample of Italian healthy subjects. Four hundred and fifteen Italian healthy subjects (252 women and 163 men) of different ages (age range 21–95 years) and educational level (from primary to university) underwent MoCA and Mini Mental State Examination (MMSE). Multiple linear regression analysis revealed that age and education significantly influenced performance on MoCA. No significant effect of gender was found. From the derived linear equation, a correction grid for MoCA raw scores was built. Inferential cut-off score, estimated using a non-parametric technique, is 15.5 and equivalent scores were computed. Correlation analysis showed a significant but weak correlation between MoCA adjusted scores with MMSE adjusted scores (r = 0.43, p 

Original languageEnglish
Pages (from-to)585-591
Number of pages7
JournalNeurological Sciences
Volume36
Issue number4
DOIs
Publication statusPublished - Apr 1 2015

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Healthy Volunteers
Population
Dementia
Linear Models
Alzheimer Disease
Regression Analysis
Education
Sensitivity and Specificity
Cognitive Dysfunction

Keywords

  • Cognitive assessment
  • Montreal Cognitive Assessment (MoCA)
  • Normative data
  • Normative values

ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health
  • Dermatology
  • Medicine(all)

Cite this

Santangelo, G., Siciliano, M., Pedone, R., Vitale, C., Falco, F., Bisogno, R., ... Trojano, L. (2015). Normative data for the Montreal Cognitive Assessment in an Italian population sample. Neurological Sciences, 36(4), 585-591. https://doi.org/10.1007/s10072-014-1995-y

Normative data for the Montreal Cognitive Assessment in an Italian population sample. / Santangelo, Gabriella; Siciliano, Mattia; Pedone, Roberto; Vitale, Carmine; Falco, Fabrizia; Bisogno, Rossella; Siano, Pietro; Barone, Paolo; Grossi, Dario; Santangelo, Franco; Trojano, Luigi.

In: Neurological Sciences, Vol. 36, No. 4, 01.04.2015, p. 585-591.

Research output: Contribution to journalArticle

Santangelo, G, Siciliano, M, Pedone, R, Vitale, C, Falco, F, Bisogno, R, Siano, P, Barone, P, Grossi, D, Santangelo, F & Trojano, L 2015, 'Normative data for the Montreal Cognitive Assessment in an Italian population sample', Neurological Sciences, vol. 36, no. 4, pp. 585-591. https://doi.org/10.1007/s10072-014-1995-y
Santangelo G, Siciliano M, Pedone R, Vitale C, Falco F, Bisogno R et al. Normative data for the Montreal Cognitive Assessment in an Italian population sample. Neurological Sciences. 2015 Apr 1;36(4):585-591. https://doi.org/10.1007/s10072-014-1995-y
Santangelo, Gabriella ; Siciliano, Mattia ; Pedone, Roberto ; Vitale, Carmine ; Falco, Fabrizia ; Bisogno, Rossella ; Siano, Pietro ; Barone, Paolo ; Grossi, Dario ; Santangelo, Franco ; Trojano, Luigi. / Normative data for the Montreal Cognitive Assessment in an Italian population sample. In: Neurological Sciences. 2015 ; Vol. 36, No. 4. pp. 585-591.
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