Nosocomial bloodstream infections among human immunodeficiency virus-infected patients: Incidence and risk factors

Nicola Petrosillo, Pierluigi Viale, Emanuele Nicastri, Claudio Arici, Enrico Bombana, Alberto Casella, Francesco Cristini, Michele De Gennaro, Ferdinando Dodi, Andrea Gabbuti, Gianni Gattuso, Laura Irato, Paolo Maggi, Federico Pallavicini, Angelo Pan, Mario Pantaleoni, Giuseppe Ippolito

Research output: Contribution to journalArticle

Abstract

To assess the incidence of nosocomial bloodstream infections (NBSIs) in human immunodeficiency virus (HIV)-infected patients, and to analyze the main associated risk factors, we performed a 1-year multicenter prospective study of patients with advanced HIV infection who were consecutively admitted to 17 Italian infectious diseases wards. As of May 1999, a total of 65 NBSIs (4.7%) occurred in 1379 admissions, for an incidence of 2.45 NBSIs per 1000 patient-days. Twenty-nine NBSIs were catheter-related bloodstream infections, with a rate of 9.6 central venous catheter-associated infections per 1000 device-days. Multivariate analysis indicated that variables independently associated with NBSIs included active injection drug use, a Karnofsky Performance Status score of

Original languageEnglish
Pages (from-to)677-685
Number of pages9
JournalClinical Infectious Diseases
Volume34
Issue number5
DOIs
Publication statusPublished - Mar 1 2002

ASJC Scopus subject areas

  • Immunology

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    Petrosillo, N., Viale, P., Nicastri, E., Arici, C., Bombana, E., Casella, A., Cristini, F., De Gennaro, M., Dodi, F., Gabbuti, A., Gattuso, G., Irato, L., Maggi, P., Pallavicini, F., Pan, A., Pantaleoni, M., & Ippolito, G. (2002). Nosocomial bloodstream infections among human immunodeficiency virus-infected patients: Incidence and risk factors. Clinical Infectious Diseases, 34(5), 677-685. https://doi.org/10.1086/338813