Not just sheer luck! Immune correlates of protection against HIV-1 infection

Luca Piacentini; Claudio Fenizia; Valentina Naddeo; Mario Clerici

doi:10.1016/j.vaccine.2007.11.062

Not just sheer luck! Immune correlates of protection against HIV-1 infection

Luca Piacentini, Claudio Fenizia, Valentina Naddeo, Mario Clerici

Fondazione Don Carlo Gnocchi Onlus

Research output: Contribution to journal › Article › peer-review

Abstract

Susceptibility to HIV infection is widely different among individuals, and it is known that individuals can be identified who are repeatedly exposed to HIV but in whom neither infection nor disease are seen. The possibility that sheer luck is not the only determinant of this phenomenon begun to be considered in 1989 when it was reported that T cell responses to HIV proteins could be detected in antibody-negative sexual partners of known HIV-positive men. In this review we will summarize the body of knowledge that stemmed from that first observation.

Original language	English
Pages (from-to)	3002-3007
Number of pages	6
Journal	Vaccine
Volume	26
Issue number	24
DOIs	https://doi.org/10.1016/j.vaccine.2007.11.062
Publication status	Published - Jun 6 2008

Keywords

AIDS
HIV-exposed seronegative individuals
Immune correlates of protection
Immunology
Resistance to infection

ASJC Scopus subject areas

Immunology
Microbiology
Virology
Infectious Diseases
Public Health, Environmental and Occupational Health
veterinary(all)

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