Several benzodiazepines are now available for clinical use although pharmacological and clinical studies have failed to show any major qualitative differences between them. The main differences between these drugs is in their pharmacokinetics and metabolism. In particular it will be discussed the problem of the formation of active metabolites and the relation between brain levels and occupancy of benzodiazepine receptor sites.
|Number of pages||14|
|Journal||Advances in the Biosciences|
|Publication status||Published - 1981|
- benzodiazepine receptors
- brain levels