Notes on kinetics and metabolism of benzodiazepines

S. Garattini, S. Caccia, M. Carli, T. Mennini

Research output: Contribution to journalArticlepeer-review


Several benzodiazepines are now available for clinical use although pharmacological and clinical studies have failed to show any major qualitative differences between them. The main differences between these drugs is in their pharmacokinetics and metabolism. In particular it will be discussed the problem of the formation of active metabolites and the relation between brain levels and occupancy of benzodiazepine receptor sites.

Original languageEnglish
Pages (from-to)351-364
Number of pages14
JournalAdvances in the Biosciences
Issue numberC
Publication statusPublished - 1981


  • benzodiazepine receptors
  • Benzodiazepines
  • brain levels
  • camazepam
  • clobazam
  • diazepam


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