TY - JOUR
T1 - Novel antihypertensive therapies
T2 - Renal sympathetic nerve ablation and carotid baroreceptor stimulation
AU - Grassi, Guido
AU - Seravalle, Gino
AU - Brambilla, Gianmaria
AU - Bombelli, Michele
AU - Dell'Oro, Raffaella
AU - Gronda, Edoardo
AU - Mancia, Giuseppe
PY - 2012/12
Y1 - 2012/12
N2 - Therapeutic interventions aimed at reducing high blood pressure still encompass a number of difficulties and limitations. This is the case particularly in resistant hypertension, i.e. a condition characterized by a very high cardiovascular risk. Carotid baroreceptor stimulation and renal sympathetic nerves ablation represent new approaches in the treatment of this condition. This paper will provide a comparison of the effects of the two procedures, highlighting their effects on blood pressure, metabolic profile, target organ damage, safety and tolerability profile.
AB - Therapeutic interventions aimed at reducing high blood pressure still encompass a number of difficulties and limitations. This is the case particularly in resistant hypertension, i.e. a condition characterized by a very high cardiovascular risk. Carotid baroreceptor stimulation and renal sympathetic nerves ablation represent new approaches in the treatment of this condition. This paper will provide a comparison of the effects of the two procedures, highlighting their effects on blood pressure, metabolic profile, target organ damage, safety and tolerability profile.
KW - Blood pressure
KW - Carotid baroreceptor stimulation
KW - End-organ damage
KW - Hypertension
KW - Insulin
KW - Interventions
KW - Renal denervation
KW - Resistant hypertension
KW - Side effects
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U2 - 10.1007/s11906-012-0312-5
DO - 10.1007/s11906-012-0312-5
M3 - Article
C2 - 23011743
AN - SCOPUS:84870499592
VL - 14
SP - 567
EP - 572
JO - Current Hypertension Reports
JF - Current Hypertension Reports
SN - 1522-6417
IS - 6
ER -