Novel antihypertensive therapies: Renal sympathetic nerve ablation and carotid baroreceptor stimulation

Guido Grassi, Gino Seravalle, Gianmaria Brambilla, Michele Bombelli, Raffaella Dell'Oro, Edoardo Gronda, Giuseppe Mancia

Research output: Contribution to journalArticlepeer-review

Abstract

Therapeutic interventions aimed at reducing high blood pressure still encompass a number of difficulties and limitations. This is the case particularly in resistant hypertension, i.e. a condition characterized by a very high cardiovascular risk. Carotid baroreceptor stimulation and renal sympathetic nerves ablation represent new approaches in the treatment of this condition. This paper will provide a comparison of the effects of the two procedures, highlighting their effects on blood pressure, metabolic profile, target organ damage, safety and tolerability profile.

Original languageEnglish
Pages (from-to)567-572
Number of pages6
JournalCurrent Hypertension Reports
Volume14
Issue number6
DOIs
Publication statusPublished - Dec 2012

Keywords

  • Blood pressure
  • Carotid baroreceptor stimulation
  • End-organ damage
  • Hypertension
  • Insulin
  • Interventions
  • Renal denervation
  • Resistant hypertension
  • Side effects

ASJC Scopus subject areas

  • Internal Medicine

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