Abstract
Therapeutic interventions aimed at reducing high blood pressure still encompass a number of difficulties and limitations. This is the case particularly in resistant hypertension, i.e. a condition characterized by a very high cardiovascular risk. Carotid baroreceptor stimulation and renal sympathetic nerves ablation represent new approaches in the treatment of this condition. This paper will provide a comparison of the effects of the two procedures, highlighting their effects on blood pressure, metabolic profile, target organ damage, safety and tolerability profile.
| Original language | English |
|---|---|
| Pages (from-to) | 567-572 |
| Number of pages | 6 |
| Journal | Current Hypertension Reports |
| Volume | 14 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - Dec 2012 |
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Keywords
- Blood pressure
- Carotid baroreceptor stimulation
- End-organ damage
- Hypertension
- Insulin
- Interventions
- Renal denervation
- Resistant hypertension
- Side effects
ASJC Scopus subject areas
- Internal Medicine
Cite this
Novel antihypertensive therapies : Renal sympathetic nerve ablation and carotid baroreceptor stimulation. / Grassi, Guido; Seravalle, Gino; Brambilla, Gianmaria; Bombelli, Michele; Dell'Oro, Raffaella; Gronda, Edoardo; Mancia, Giuseppe.
In: Current Hypertension Reports, Vol. 14, No. 6, 12.2012, p. 567-572.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Novel antihypertensive therapies
T2 - Renal sympathetic nerve ablation and carotid baroreceptor stimulation
AU - Grassi, Guido
AU - Seravalle, Gino
AU - Brambilla, Gianmaria
AU - Bombelli, Michele
AU - Dell'Oro, Raffaella
AU - Gronda, Edoardo
AU - Mancia, Giuseppe
PY - 2012/12
Y1 - 2012/12
N2 - Therapeutic interventions aimed at reducing high blood pressure still encompass a number of difficulties and limitations. This is the case particularly in resistant hypertension, i.e. a condition characterized by a very high cardiovascular risk. Carotid baroreceptor stimulation and renal sympathetic nerves ablation represent new approaches in the treatment of this condition. This paper will provide a comparison of the effects of the two procedures, highlighting their effects on blood pressure, metabolic profile, target organ damage, safety and tolerability profile.
AB - Therapeutic interventions aimed at reducing high blood pressure still encompass a number of difficulties and limitations. This is the case particularly in resistant hypertension, i.e. a condition characterized by a very high cardiovascular risk. Carotid baroreceptor stimulation and renal sympathetic nerves ablation represent new approaches in the treatment of this condition. This paper will provide a comparison of the effects of the two procedures, highlighting their effects on blood pressure, metabolic profile, target organ damage, safety and tolerability profile.
KW - Blood pressure
KW - Carotid baroreceptor stimulation
KW - End-organ damage
KW - Hypertension
KW - Insulin
KW - Interventions
KW - Renal denervation
KW - Resistant hypertension
KW - Side effects
UR - http://www.scopus.com/inward/record.url?scp=84870499592&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84870499592&partnerID=8YFLogxK
U2 - 10.1007/s11906-012-0312-5
DO - 10.1007/s11906-012-0312-5
M3 - Article
C2 - 23011743
AN - SCOPUS:84870499592
VL - 14
SP - 567
EP - 572
JO - Current Hypertension Reports
JF - Current Hypertension Reports
SN - 1522-6417
IS - 6
ER -