TY - JOUR
T1 - Novel biotinylated bile acid amphiphiles
T2 - Micellar aggregates formation and interaction with hepatocytes
AU - Rizzi, Luca
AU - Braschi, Marta
AU - Colombo, Miriam
AU - Vaiana, Nadia
AU - Tibolla, Gianpaolo
AU - Norata, Giuseppe Danilo
AU - Catapano, Alberico Luigi
AU - Romeo, Sergio
AU - Prosperi, Davide
PY - 2011/4/21
Y1 - 2011/4/21
N2 - Amphiphilic bile acids linked through an oligoethylene glycol to a biotin moiety were synthesized and shown to create micellar structures in aqueous environment, interact with avidin and be efficiently incorporated into hepatocyte cells, suggesting their potential as a drug delivery system against liver diseases.
AB - Amphiphilic bile acids linked through an oligoethylene glycol to a biotin moiety were synthesized and shown to create micellar structures in aqueous environment, interact with avidin and be efficiently incorporated into hepatocyte cells, suggesting their potential as a drug delivery system against liver diseases.
UR - http://www.scopus.com/inward/record.url?scp=79953225908&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79953225908&partnerID=8YFLogxK
U2 - 10.1039/c0ob00878h
DO - 10.1039/c0ob00878h
M3 - Article
C2 - 21373679
AN - SCOPUS:79953225908
VL - 9
SP - 2899
EP - 2905
JO - Organic and Biomolecular Chemistry
JF - Organic and Biomolecular Chemistry
SN - 1477-0520
IS - 8
ER -