Novel cancer therapies for advanced cutaneous melanoma: The added value of radiomics in the decision making process-A systematic review

Antonino Guerrisi, Emiliano Loi, Sara Ungania, Michelangelo Russillo, Vicente Bruzzaniti, Fulvia Elia, Flora Desiderio, Raffaella Marconi, Francesco Maria Solivetti, Lidia Strigari

Research output: Contribution to journalReview article

Abstract

Advanced malignant melanoma represents a public health matter due to its rising incidence and aggressiveness. Novel therapies such as immunotherapy are showing promising results with improved progression free and overall survival in melanoma patients. However, novel targeted and immunotherapies could generate atypical patterns of response which are nowadays a big challenge since imaging criteria (ie Recist 1.1) have not been proven to be always reliable to assess response. Radiomics and in particular texture analysis (TA) represent new quantitative methodologies which could reduce the impact of these limitations providing most robust data in support of clinical decision process. The aim of this paper was to review the state of the art of radiomics/TA when it is applied to the imaging of metastatic melanoma patients.

Original languageEnglish
JournalCancer Medicine
DOIs
Publication statusE-pub ahead of print - Jan 17 2019

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