Terapie innovative in oncologia

Translated title of the contribution: Novel molecular-targeting treatments in oncology

Barbara Capaccetti, Paola Bonginelli, Roberta Sarmiento, Massimo Fanelli, Raffaele Longo, Domenico Gattuso, Giampietro Gasparini

Research output: Contribution to journalArticle

Abstract

The improved knowledge of the key molecular mechanisms involved in cell transformation and tumor progression allows to the identification of new therapeutic targets for anticancer therapy. Several molecular-targeting compounds have been developed, capable to selectively interfire with tumor angiogenesis-, receptors with tyrosin-chinase activity, specific tumor growth factors. A rationale selection of the patients as well as an appropriate monitoring of pharmacodynamics effects of molecular-targeting compounds need of the availability of surrogate markers, assessable in tumor tissue of circulating blood.

Original languageItalian
Pages (from-to)602-609
Number of pages8
JournalRecenti Progressi in Medicina
Volume93
Issue number11
Publication statusPublished - Nov 2002

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Neoplasms
Patient Selection
Intercellular Signaling Peptides and Proteins
Biomarkers
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Capaccetti, B., Bonginelli, P., Sarmiento, R., Fanelli, M., Longo, R., Gattuso, D., & Gasparini, G. (2002). Terapie innovative in oncologia. Recenti Progressi in Medicina, 93(11), 602-609.

Terapie innovative in oncologia. / Capaccetti, Barbara; Bonginelli, Paola; Sarmiento, Roberta; Fanelli, Massimo; Longo, Raffaele; Gattuso, Domenico; Gasparini, Giampietro.

In: Recenti Progressi in Medicina, Vol. 93, No. 11, 11.2002, p. 602-609.

Research output: Contribution to journalArticle

Capaccetti, B, Bonginelli, P, Sarmiento, R, Fanelli, M, Longo, R, Gattuso, D & Gasparini, G 2002, 'Terapie innovative in oncologia', Recenti Progressi in Medicina, vol. 93, no. 11, pp. 602-609.
Capaccetti B, Bonginelli P, Sarmiento R, Fanelli M, Longo R, Gattuso D et al. Terapie innovative in oncologia. Recenti Progressi in Medicina. 2002 Nov;93(11):602-609.
Capaccetti, Barbara ; Bonginelli, Paola ; Sarmiento, Roberta ; Fanelli, Massimo ; Longo, Raffaele ; Gattuso, Domenico ; Gasparini, Giampietro. / Terapie innovative in oncologia. In: Recenti Progressi in Medicina. 2002 ; Vol. 93, No. 11. pp. 602-609.
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