Terapie innovative in oncologia

Translated title of the contribution: Novel molecular-targeting treatments in oncology

Barbara Capaccetti, Paola Bonginelli, Roberta Sarmiento, Massimo Fanelli, Raffaele Longo, Domenico Gattuso, Giampietro Gasparini

Research output: Contribution to journalArticlepeer-review

Abstract

The improved knowledge of the key molecular mechanisms involved in cell transformation and tumor progression allows to the identification of new therapeutic targets for anticancer therapy. Several molecular-targeting compounds have been developed, capable to selectively interfire with tumor angiogenesis-, receptors with tyrosin-chinase activity, specific tumor growth factors. A rationale selection of the patients as well as an appropriate monitoring of pharmacodynamics effects of molecular-targeting compounds need of the availability of surrogate markers, assessable in tumor tissue of circulating blood.

Translated title of the contributionNovel molecular-targeting treatments in oncology
Original languageItalian
Pages (from-to)602-609
Number of pages8
JournalRecenti Progressi in Medicina
Volume93
Issue number11
Publication statusPublished - Nov 2002

ASJC Scopus subject areas

  • Medicine(all)

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