Novel therapeutic targets for allergic airway disease in children

Alessandro Giallongo, Giuseppe Fabio Parisi, Amelia Licari, Giulio Pulvirenti, Caterina Cuppari, Carmelo Salpietro, Gian Luigi Marseglia, Salvatore Leonardi

Research output: Contribution to journalReview articlepeer-review


The aim of precision medicine is setting up targeted therapies for selected patients that would ideally have high effectiveness and few side effects. This is made possible by targeted therapy drugs that selectively act on a specific pathway. Precision medicine is spreading to many medical specialties, and there is increasing interest in the context of allergic airway diseases, such as allergic rhinitis, chronic rhinosinusitis, and asthma. This review is an update of new targets in the treatment of childhood allergic upper airway diseases and asthma, including the most recent biologic drugs that have already been licensed or are in the pipeline to be tested with children.

Original languageEnglish
Article number212590
JournalDrugs in Context
Publication statusPublished - Jan 1 2019


  • Allergic airway disease
  • Allergic rhinitis
  • Asthma
  • Biologics
  • Children
  • Chronic rhinosinusitis
  • Immunotherapy

ASJC Scopus subject areas

  • Molecular Medicine
  • Pharmacology


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