Novel ultrasound-based methods to assess liver disease

The game has just begun

Annalisa Berzigotti, Giovanna Ferraioli, Simona Bota, Odd Helge Gilja, Christoph F Dietrich

Research output: Contribution to journalReview article

Abstract

In the last 10 years the availability of ultrasound elastography allowed to diagnose and stage liver fibrosis in a non-invasive way and changed the clinical practice of hepatology. Newer ultrasound-based techniques to evaluate properties of the liver tissue other than fibrosis are emerging and will lead to a more complete characterization of the full spectrum of diffuse and focal liver disease. Since these methods are currently undergoing validation and go beyond elastography for liver tissue evaluation, they were not included in the recent guidelines regarding elastography issued by the European Federation of Societies in Ultrasound in Medicine and Biology. In this review paper, we outline the major advances in the field of ultrasound for liver applications, with special emphasis on techniques that could soon be part of the future armamentarium of ultrasound specialists devoted to the assessment of liver disease. Specifically, we discuss current and future ultrasound assessment of steatosis, spleen stiffness for portal hypertension, and elastography for the evaluation of focal liver lesions; we also provide a short glimpse into the next generation of ultrasound diagnostic methods.

Original languageEnglish
Pages (from-to)107-112
Number of pages6
JournalDigestive and Liver Disease
Volume50
Issue number2
DOIs
Publication statusPublished - Feb 2018

Fingerprint

Elasticity Imaging Techniques
Liver Diseases
Liver
Portal Hypertension
Gastroenterology
Liver Cirrhosis
Ultrasonography
Fibrosis
Spleen
Medicine
Guidelines

Keywords

  • Elasticity Imaging Techniques/trends
  • Fatty Liver/diagnostic imaging
  • Humans
  • Liver/diagnostic imaging
  • Liver Cirrhosis/diagnostic imaging
  • Spleen/diagnostic imaging

Cite this

Novel ultrasound-based methods to assess liver disease : The game has just begun. / Berzigotti, Annalisa; Ferraioli, Giovanna; Bota, Simona; Gilja, Odd Helge; Dietrich, Christoph F.

In: Digestive and Liver Disease, Vol. 50, No. 2, 02.2018, p. 107-112.

Research output: Contribution to journalReview article

Berzigotti, Annalisa ; Ferraioli, Giovanna ; Bota, Simona ; Gilja, Odd Helge ; Dietrich, Christoph F. / Novel ultrasound-based methods to assess liver disease : The game has just begun. In: Digestive and Liver Disease. 2018 ; Vol. 50, No. 2. pp. 107-112.
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abstract = "In the last 10 years the availability of ultrasound elastography allowed to diagnose and stage liver fibrosis in a non-invasive way and changed the clinical practice of hepatology. Newer ultrasound-based techniques to evaluate properties of the liver tissue other than fibrosis are emerging and will lead to a more complete characterization of the full spectrum of diffuse and focal liver disease. Since these methods are currently undergoing validation and go beyond elastography for liver tissue evaluation, they were not included in the recent guidelines regarding elastography issued by the European Federation of Societies in Ultrasound in Medicine and Biology. In this review paper, we outline the major advances in the field of ultrasound for liver applications, with special emphasis on techniques that could soon be part of the future armamentarium of ultrasound specialists devoted to the assessment of liver disease. Specifically, we discuss current and future ultrasound assessment of steatosis, spleen stiffness for portal hypertension, and elastography for the evaluation of focal liver lesions; we also provide a short glimpse into the next generation of ultrasound diagnostic methods.",
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AU - Dietrich, Christoph F

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N2 - In the last 10 years the availability of ultrasound elastography allowed to diagnose and stage liver fibrosis in a non-invasive way and changed the clinical practice of hepatology. Newer ultrasound-based techniques to evaluate properties of the liver tissue other than fibrosis are emerging and will lead to a more complete characterization of the full spectrum of diffuse and focal liver disease. Since these methods are currently undergoing validation and go beyond elastography for liver tissue evaluation, they were not included in the recent guidelines regarding elastography issued by the European Federation of Societies in Ultrasound in Medicine and Biology. In this review paper, we outline the major advances in the field of ultrasound for liver applications, with special emphasis on techniques that could soon be part of the future armamentarium of ultrasound specialists devoted to the assessment of liver disease. Specifically, we discuss current and future ultrasound assessment of steatosis, spleen stiffness for portal hypertension, and elastography for the evaluation of focal liver lesions; we also provide a short glimpse into the next generation of ultrasound diagnostic methods.

AB - In the last 10 years the availability of ultrasound elastography allowed to diagnose and stage liver fibrosis in a non-invasive way and changed the clinical practice of hepatology. Newer ultrasound-based techniques to evaluate properties of the liver tissue other than fibrosis are emerging and will lead to a more complete characterization of the full spectrum of diffuse and focal liver disease. Since these methods are currently undergoing validation and go beyond elastography for liver tissue evaluation, they were not included in the recent guidelines regarding elastography issued by the European Federation of Societies in Ultrasound in Medicine and Biology. In this review paper, we outline the major advances in the field of ultrasound for liver applications, with special emphasis on techniques that could soon be part of the future armamentarium of ultrasound specialists devoted to the assessment of liver disease. Specifically, we discuss current and future ultrasound assessment of steatosis, spleen stiffness for portal hypertension, and elastography for the evaluation of focal liver lesions; we also provide a short glimpse into the next generation of ultrasound diagnostic methods.

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KW - Humans

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KW - Liver Cirrhosis/diagnostic imaging

KW - Spleen/diagnostic imaging

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