TY - JOUR
T1 - NT-proBNP, IGF-I and survival in patients with chronic heart failure
AU - Petretta, Mario
AU - Colao, Annamaria
AU - Sardu, Celestino
AU - Scopacasa, Franco
AU - Marzullo, Paolo
AU - Pivonello, Rosario
AU - Fontanella, Luca
AU - de Caterina, Maurizio
AU - de Simone, Adriano
AU - Bonaduce, Domenico
PY - 2007/8
Y1 - 2007/8
N2 - Objective: Growth hormone (GH) resistance with a reduction of insulin-like growth factor-I (IGF-I) serum concentrations seems to be implicated in the catabolic process associated with chronic heart failure (CHF). However, data concerning the prognostic value of these alterations in CHF patients without cachexia are scant. In this study, we aimed to determine in CHF patients the prognostic value of IGF-I/GH ratio and its relationships with N-terminal brain natriuretic peptide (NT-proBNP), a known marker of prognosis in these patients. Design: We enrolled 82 non-cachectic patients, mean age 61 ± 13 years, with ejection fraction
AB - Objective: Growth hormone (GH) resistance with a reduction of insulin-like growth factor-I (IGF-I) serum concentrations seems to be implicated in the catabolic process associated with chronic heart failure (CHF). However, data concerning the prognostic value of these alterations in CHF patients without cachexia are scant. In this study, we aimed to determine in CHF patients the prognostic value of IGF-I/GH ratio and its relationships with N-terminal brain natriuretic peptide (NT-proBNP), a known marker of prognosis in these patients. Design: We enrolled 82 non-cachectic patients, mean age 61 ± 13 years, with ejection fraction
KW - Chronic heart failure
KW - GH
KW - IGF-I
KW - NT-proBNP
KW - Prognosis
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U2 - 10.1016/j.ghir.2007.01.020
DO - 10.1016/j.ghir.2007.01.020
M3 - Article
C2 - 17383209
AN - SCOPUS:34547141149
VL - 17
SP - 288
EP - 296
JO - Endocrinology and Metabolism, Supplement
JF - Endocrinology and Metabolism, Supplement
SN - 1096-6374
IS - 4
ER -