Nuclear magnetic resonance approaches to brain function studies

S. Capuani, G. Garreffa, M. A. Macrì, S. Mangia, F. Di Salle, B. Maraviglia

Research output: Contribution to journalArticlepeer-review


The fast developing and newly emerging nuclear magnetic resonance methods for functional brain imaging are discussed. The main features of blood-oxygen-level-dependent (BOLD) imaging and perfusion imaging are exposed together with their limitations. The combination of localized spectroscopy with magnetic resonance imaging (MRI) and neuronal activation provide the crucial metabolic information, which is complementary to the physiological data given by BOLD and perfusion imaging. Finally, the diffusion tensor imaging and the nonlinear MRI, with the perspective of getting information about the "architecture" of the axonal connections and of the macrostructures are discussed.

Original languageEnglish
Pages (from-to)85-96
Number of pages12
JournalApplied Magnetic Resonance
Issue number1-2
Publication statusPublished - 2001

ASJC Scopus subject areas

  • Spectroscopy
  • Atomic and Molecular Physics, and Optics


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