Progress in the instrumentation and synthesis of new radiopharmaceuticals have allowed the current use of nuclear medicine techniques in the diagnostic assessment of many neurological diseases, in which the biochemistry and physiology of the brain can be studied in vivo. PET compares very well with other neuroimaging techniques (CT, MRI, contrast angiography) thanks to its high spatial resolution and the large number of functional parameters that can be assessed. However, the scarce distribution and high cost of PET negatively affect its use in neurological pathologies with a high incidence and social relevance, such as vascular, neoplastic, and degenerative diseases of the central nervous system. A pivotal role in nuclear neuroimaging today is assumed by brain SPET, which allows functional imaging of an increasing number of parameters in normal and diseased brain tissues in almost all diseases of the brain. The chapter reports the state of the art of the main applications of SPET and other scintigraphic techniques, particularly those frequently adopted by the neurologist in the instrumental workup of patients with neurological and neurosurgical problems.
|Translated title of the contribution||Nuclear medicine in neurology|
|Number of pages||12|
|Publication status||Published - 1999|
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