Abstract
By means of a silver staining method, Nucleolar Organizer Region-associated proteins (NORs) have been evaluated on paraffin sections of a series of 58 ultrasound-guided liver biopsy specimens. These included 12 normal livers, 12 cirrhotic livers, 12 cases of chronic hepatitis and 22 cases of hepatocellular carcinoma. A significant difference (P less than 0.001) was found between the mean AgNOR scores of the normal and pathological biopsies, and between the non-neoplastic and the carcinomatous lesions. The authors suggest that AgNOR counts, in combination with conventional histocytological criteria, may be a useful method in the diagnosis of liver diseases.
| Original language | English |
|---|---|
| Pages (from-to) | 653-662 |
| Number of pages | 10 |
| Journal | Pathologica |
| Volume | 82 |
| Issue number | 1082 |
| Publication status | Published - Nov 1990 |
ASJC Scopus subject areas
- Pathology and Forensic Medicine