Abstract
An immunocytochemical technique that allows visualization of two antigens in the same neurons was used to verify the possibility that some neocortical pyramidal neurons contain both glutamate (Glu) and substance P (SP) immunoreactivity. The results show that a large fraction of SP-positive pyramidal neurons are also Glu-positive, and indicate that in a small population of cortical neurons a fast excitatory synaptic transmitter and a slow peptidic modulator coexist.
Original language | English |
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Pages (from-to) | 140-143 |
Number of pages | 4 |
Journal | Brain Research |
Volume | 599 |
Issue number | 1 |
DOIs | |
Publication status | Published - Dec 18 1992 |
Keywords
- Cerebral cortex
- Glutamate
- Pyramidal neuron
- Substance P
ASJC Scopus subject areas
- Developmental Biology
- Molecular Biology
- Clinical Neurology
- Neuroscience(all)