Nutraceuticals and chondroprotective agents for the treatment of osteoarthritis: A narrative review. A controversial resource in the treatment of osteoarthritis

V. Sansone, O. Consonni, E. Maiorano

Research output: Contribution to journalArticle


There are many dietary supplements, chondroprotective agents, disease-modifying agents and nutraceuticals that have been developed and promoted for treating patients affected by osteoarthritis (OA). They can be, and often are, marketed without undergoing a rigorous scientific evaluation. In the literature several in vitro- or in vivo-trials concerning these compounds can be found, but there is a lack of high-quality, long-term, prospective, comparative studies able to demonstrate unequivocally their effectiveness in the treatment of OA. This is a narrative review concerning the commonest chondroprotective agents found on the market, and assesses whether, on the basis of the current literature, these agents may have a role in the treatment of OA.

Original languageEnglish
Pages (from-to)61-72
Number of pages12
JournalMinerva Ortopedica e Traumatologica
Issue number1
Publication statusPublished - 2014



  • Arthritis
  • Cartilage
  • Glucosamine
  • Osteoarthritis
  • Vitamin C
  • Vitamin D

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine

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