Nutrient dietary patterns and gastric cancer risk in Italy

Paola Bertuccio, Valeria Edefonti, Francesca Bravi, Monica Ferraroni, Claudio Pelucchi, Eva Negri, Adriano Decarli, Carlo La Vecchia

Research output: Contribution to journalArticle

Abstract

Background: There have been several studies on diet and gastric cancer, but only a few investigations have considered the role of dietary patterns. Methods: We investigated gastric cancer risk in relation to dietary patterns in a case-control study conducted in northern Italy between 1997 and 2007, including 230 patients with incident, histologically confirmed gastric cancer and 547 frequency-matched controls, admitted to the same hospitals as cases, with acute nonneoplastic conditions. Dietary habits were investigated through a validated food frequency questionnaire including 78 foods and beverages. We identified a posteriori dietary patterns on a selected set of 28 micro- and macro-nutrients through an exploratory principal component factor analysis. We estimated the odds ratios (OR) and the corresponding 95% confidence intervals (95% CI) using conditional logistic regression models on quartiles of factor scores. Results: We identified four major dietary patterns, named "animal products", "vitamins and fiber", "vegetable unsaturated fatty acids", and "starch-rich". We observed a positive association between gastric cancer risk and the "animal products" (OR, 2.13; 95% CI, 1.34-3.40, for the highest versus the lowest score quartile) and the "starch-rich" (OR, 1.67; 95% CI, 1.01-2.77) dietary patterns. The "vitamins and fiber" pattern (OR, 0.60; 95% CI, 0.37-0.99) was inversely associated with gastric cancer, whereas no significant association emerged with the "vegetable unsaturated fatty acids" pattern (OR, 0.89; 95% CI, 0.56-1.42). Conclusions: Our analysis suggests a protective effect against gastric cancer risk of dietary patterns rich in fruits and vegetables, and a positive association of dietary patterns rich in meats and animal fats and starchy foods.

Original languageEnglish
Pages (from-to)2882-2886
Number of pages5
JournalCancer Epidemiology Biomarkers and Prevention
Volume18
Issue number11
DOIs
Publication statusPublished - Nov 2009

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Italy
Stomach Neoplasms
Food
Odds Ratio
Confidence Intervals
Vegetables
Unsaturated Fatty Acids
Vitamins
Starch
Logistic Models
Food and Beverages
Feeding Behavior
Principal Component Analysis
Meat
Statistical Factor Analysis
Case-Control Studies
Fruit
Fats
Diet

ASJC Scopus subject areas

  • Epidemiology
  • Oncology

Cite this

Bertuccio, P., Edefonti, V., Bravi, F., Ferraroni, M., Pelucchi, C., Negri, E., ... La Vecchia, C. (2009). Nutrient dietary patterns and gastric cancer risk in Italy. Cancer Epidemiology Biomarkers and Prevention, 18(11), 2882-2886. https://doi.org/10.1158/1055-9965.EPI-09-0782

Nutrient dietary patterns and gastric cancer risk in Italy. / Bertuccio, Paola; Edefonti, Valeria; Bravi, Francesca; Ferraroni, Monica; Pelucchi, Claudio; Negri, Eva; Decarli, Adriano; La Vecchia, Carlo.

In: Cancer Epidemiology Biomarkers and Prevention, Vol. 18, No. 11, 11.2009, p. 2882-2886.

Research output: Contribution to journalArticle

Bertuccio, P, Edefonti, V, Bravi, F, Ferraroni, M, Pelucchi, C, Negri, E, Decarli, A & La Vecchia, C 2009, 'Nutrient dietary patterns and gastric cancer risk in Italy', Cancer Epidemiology Biomarkers and Prevention, vol. 18, no. 11, pp. 2882-2886. https://doi.org/10.1158/1055-9965.EPI-09-0782
Bertuccio P, Edefonti V, Bravi F, Ferraroni M, Pelucchi C, Negri E et al. Nutrient dietary patterns and gastric cancer risk in Italy. Cancer Epidemiology Biomarkers and Prevention. 2009 Nov;18(11):2882-2886. https://doi.org/10.1158/1055-9965.EPI-09-0782
Bertuccio, Paola ; Edefonti, Valeria ; Bravi, Francesca ; Ferraroni, Monica ; Pelucchi, Claudio ; Negri, Eva ; Decarli, Adriano ; La Vecchia, Carlo. / Nutrient dietary patterns and gastric cancer risk in Italy. In: Cancer Epidemiology Biomarkers and Prevention. 2009 ; Vol. 18, No. 11. pp. 2882-2886.
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