Nutritional status and dementia in oldest-old women

G. Ravaglia, D. De Ronchi, P. Forti, F. Maioli, A. Cicognani, C. R. Scali, L. Pratelli, A. Pizzoferrato, M. Bernardi, G. Gasbarrini

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

As in the literature data about the relationships between dementia and nutritional indices in oldest-old people are scarce, we evaluated the nutritional and cognitive status of 27 non-hospitalized, over 90-year-old women living in Bologna. Among them, 15 subjects were demented according to the guidelines of the American Psychiatric Association (DSM-III-R). Body mass index (BMI) was calculated as weight/height2 (kg/m2). Fat mass percentage (FM%) was calculated from anthropometric measurements according to the Durnin-Womersley' formula. Serum albumin, vitamin D (1,25(OH)2D), and insulin-like-growth factor 1 (IGF-1) were also measured. No difference between demented and non demented people was found for BMI and serum albumin, whereas demented women had smaller values of FM%, 1,25(OH)2D and IGF-1. As demented women were also significantly older and less literate than normal women, the statistical significance of these differences was retested by ANOVA variance analysis adjusting for age and years of education. FM% (p = 0.017), 1,25(OH)2D (p = 0.004) and IGF-1 (p = 0.004) were all confirmed being significantly reduced in demented women. The conclusions are: (i) demented over 90-year-old women have an increased risk of malnutrition; (ii) although usually used in clinical routine, BMI and serum albumin seem to be less sensible nutritional indicators than the less commonly evaluated skinfold thicknesses, vitamin D and IGF-1.

Original languageEnglish
Pages (from-to)427-430
Number of pages4
JournalArchives of Gerontology and Geriatrics
Volume27
Issue numberSUPPL. 6
Publication statusPublished - 1998

Fingerprint

Nutritional Status
dementia
Dementia
Somatomedins
Serum Albumin
Body Mass Index
Fats
Vitamin D
Analysis of Variance
Skinfold Thickness
Nutrition Assessment
statistical significance
Malnutrition
Diagnostic and Statistical Manual of Mental Disorders
Guidelines
Education
Weights and Measures
Values
education

Keywords

  • Dementia
  • Nutritional status
  • Oldest-olds
  • Vitamin D

ASJC Scopus subject areas

  • Ageing
  • Medicine(all)

Cite this

Ravaglia, G., De Ronchi, D., Forti, P., Maioli, F., Cicognani, A., Scali, C. R., ... Gasbarrini, G. (1998). Nutritional status and dementia in oldest-old women. Archives of Gerontology and Geriatrics, 27(SUPPL. 6), 427-430.

Nutritional status and dementia in oldest-old women. / Ravaglia, G.; De Ronchi, D.; Forti, P.; Maioli, F.; Cicognani, A.; Scali, C. R.; Pratelli, L.; Pizzoferrato, A.; Bernardi, M.; Gasbarrini, G.

In: Archives of Gerontology and Geriatrics, Vol. 27, No. SUPPL. 6, 1998, p. 427-430.

Research output: Contribution to journalArticle

Ravaglia, G, De Ronchi, D, Forti, P, Maioli, F, Cicognani, A, Scali, CR, Pratelli, L, Pizzoferrato, A, Bernardi, M & Gasbarrini, G 1998, 'Nutritional status and dementia in oldest-old women', Archives of Gerontology and Geriatrics, vol. 27, no. SUPPL. 6, pp. 427-430.
Ravaglia G, De Ronchi D, Forti P, Maioli F, Cicognani A, Scali CR et al. Nutritional status and dementia in oldest-old women. Archives of Gerontology and Geriatrics. 1998;27(SUPPL. 6):427-430.
Ravaglia, G. ; De Ronchi, D. ; Forti, P. ; Maioli, F. ; Cicognani, A. ; Scali, C. R. ; Pratelli, L. ; Pizzoferrato, A. ; Bernardi, M. ; Gasbarrini, G. / Nutritional status and dementia in oldest-old women. In: Archives of Gerontology and Geriatrics. 1998 ; Vol. 27, No. SUPPL. 6. pp. 427-430.
@article{0eea5405e3b645dfa7987383a353b13c,
title = "Nutritional status and dementia in oldest-old women",
abstract = "As in the literature data about the relationships between dementia and nutritional indices in oldest-old people are scarce, we evaluated the nutritional and cognitive status of 27 non-hospitalized, over 90-year-old women living in Bologna. Among them, 15 subjects were demented according to the guidelines of the American Psychiatric Association (DSM-III-R). Body mass index (BMI) was calculated as weight/height2 (kg/m2). Fat mass percentage (FM{\%}) was calculated from anthropometric measurements according to the Durnin-Womersley' formula. Serum albumin, vitamin D (1,25(OH)2D), and insulin-like-growth factor 1 (IGF-1) were also measured. No difference between demented and non demented people was found for BMI and serum albumin, whereas demented women had smaller values of FM{\%}, 1,25(OH)2D and IGF-1. As demented women were also significantly older and less literate than normal women, the statistical significance of these differences was retested by ANOVA variance analysis adjusting for age and years of education. FM{\%} (p = 0.017), 1,25(OH)2D (p = 0.004) and IGF-1 (p = 0.004) were all confirmed being significantly reduced in demented women. The conclusions are: (i) demented over 90-year-old women have an increased risk of malnutrition; (ii) although usually used in clinical routine, BMI and serum albumin seem to be less sensible nutritional indicators than the less commonly evaluated skinfold thicknesses, vitamin D and IGF-1.",
keywords = "Dementia, Nutritional status, Oldest-olds, Vitamin D",
author = "G. Ravaglia and {De Ronchi}, D. and P. Forti and F. Maioli and A. Cicognani and Scali, {C. R.} and L. Pratelli and A. Pizzoferrato and M. Bernardi and G. Gasbarrini",
year = "1998",
language = "English",
volume = "27",
pages = "427--430",
journal = "Archives of Gerontology and Geriatrics",
issn = "0167-4943",
publisher = "Elsevier Ireland Ltd",
number = "SUPPL. 6",

}

TY - JOUR

T1 - Nutritional status and dementia in oldest-old women

AU - Ravaglia, G.

AU - De Ronchi, D.

AU - Forti, P.

AU - Maioli, F.

AU - Cicognani, A.

AU - Scali, C. R.

AU - Pratelli, L.

AU - Pizzoferrato, A.

AU - Bernardi, M.

AU - Gasbarrini, G.

PY - 1998

Y1 - 1998

N2 - As in the literature data about the relationships between dementia and nutritional indices in oldest-old people are scarce, we evaluated the nutritional and cognitive status of 27 non-hospitalized, over 90-year-old women living in Bologna. Among them, 15 subjects were demented according to the guidelines of the American Psychiatric Association (DSM-III-R). Body mass index (BMI) was calculated as weight/height2 (kg/m2). Fat mass percentage (FM%) was calculated from anthropometric measurements according to the Durnin-Womersley' formula. Serum albumin, vitamin D (1,25(OH)2D), and insulin-like-growth factor 1 (IGF-1) were also measured. No difference between demented and non demented people was found for BMI and serum albumin, whereas demented women had smaller values of FM%, 1,25(OH)2D and IGF-1. As demented women were also significantly older and less literate than normal women, the statistical significance of these differences was retested by ANOVA variance analysis adjusting for age and years of education. FM% (p = 0.017), 1,25(OH)2D (p = 0.004) and IGF-1 (p = 0.004) were all confirmed being significantly reduced in demented women. The conclusions are: (i) demented over 90-year-old women have an increased risk of malnutrition; (ii) although usually used in clinical routine, BMI and serum albumin seem to be less sensible nutritional indicators than the less commonly evaluated skinfold thicknesses, vitamin D and IGF-1.

AB - As in the literature data about the relationships between dementia and nutritional indices in oldest-old people are scarce, we evaluated the nutritional and cognitive status of 27 non-hospitalized, over 90-year-old women living in Bologna. Among them, 15 subjects were demented according to the guidelines of the American Psychiatric Association (DSM-III-R). Body mass index (BMI) was calculated as weight/height2 (kg/m2). Fat mass percentage (FM%) was calculated from anthropometric measurements according to the Durnin-Womersley' formula. Serum albumin, vitamin D (1,25(OH)2D), and insulin-like-growth factor 1 (IGF-1) were also measured. No difference between demented and non demented people was found for BMI and serum albumin, whereas demented women had smaller values of FM%, 1,25(OH)2D and IGF-1. As demented women were also significantly older and less literate than normal women, the statistical significance of these differences was retested by ANOVA variance analysis adjusting for age and years of education. FM% (p = 0.017), 1,25(OH)2D (p = 0.004) and IGF-1 (p = 0.004) were all confirmed being significantly reduced in demented women. The conclusions are: (i) demented over 90-year-old women have an increased risk of malnutrition; (ii) although usually used in clinical routine, BMI and serum albumin seem to be less sensible nutritional indicators than the less commonly evaluated skinfold thicknesses, vitamin D and IGF-1.

KW - Dementia

KW - Nutritional status

KW - Oldest-olds

KW - Vitamin D

UR - http://www.scopus.com/inward/record.url?scp=11544329372&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=11544329372&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:11544329372

VL - 27

SP - 427

EP - 430

JO - Archives of Gerontology and Geriatrics

JF - Archives of Gerontology and Geriatrics

SN - 0167-4943

IS - SUPPL. 6

ER -