Nutritional status of outpatients with systemic immunoglobulin light-chain amyloidosis

Riccardo Caccialanza; Giovanni Palladini; Catherine Klersy; Hellas Cena; Christina Vagia; Barbara Cameletti; Paola Russo; Francesca Lavatelli; Giampaolo Merlini

Nutritional status of outpatients with systemic immunoglobulin light-chain amyloidosis

Riccardo Caccialanza, Giovanni Palladini, Catherine Klersy, Hellas Cena, Christina Vagia, Barbara Cameletti, Paola Russo, Francesca Lavatelli, Giampaolo Merlini

IRCCS Fondazione Policlinico San Matteo

Research output: Contribution to journal › Article › peer-review

Abstract

Background: Maintenance of a good nutritional status is associated with prolonged survival in many chronic diseases. To date, the nutritional status of outpatients with immunoglobulin light-chain (AL) amyloidosis has not been evaluated. Objective: The aims of this study were to obtain information regarding the nutritional status of AL amyloidosis outpatients and to investigate its prognostic role. Design: One hundred six consecutive patients with histologically confirmed AL amyloidosis were enrolled. Anthropometric, biochemical, and clinical variables were measured. The Kaplan-Meier method was used to calculate survival. A Cox proportional hazard model was constructed to evaluate the prognostic effect of the nutritional variables. Results: Unintentional weight loss (median: 11.3%; range: 2.6-34% of usual nonedematous body weight) was documented in 58 subjects (54.7%). Body mass index (BMI; in kg/m²) was

Original language	English
Pages (from-to)	350-354
Number of pages	5
Journal	American Journal of Clinical Nutrition
Volume	83
Issue number	2
Publication status	Published - Feb 1 2006

Keywords

Amyloidosis
Nutritional status
Outpatients
Prognosis
Survival
Weight loss

ASJC Scopus subject areas

Medicine (miscellaneous)
Food Science

Cite this

Nutritional status of outpatients with systemic immunoglobulin light-chain amyloidosis. / Caccialanza, Riccardo ; Palladini, Giovanni ; Klersy, Catherine; Cena, Hellas; Vagia, Christina; Cameletti, Barbara; Russo, Paola; Lavatelli, Francesca ; Merlini, Giampaolo.

In: American Journal of Clinical Nutrition, Vol. 83, No. 2, 01.02.2006, p. 350-354.

Research output: Contribution to journal › Article › peer-review

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abstract = "Background: Maintenance of a good nutritional status is associated with prolonged survival in many chronic diseases. To date, the nutritional status of outpatients with immunoglobulin light-chain (AL) amyloidosis has not been evaluated. Objective: The aims of this study were to obtain information regarding the nutritional status of AL amyloidosis outpatients and to investigate its prognostic role. Design: One hundred six consecutive patients with histologically confirmed AL amyloidosis were enrolled. Anthropometric, biochemical, and clinical variables were measured. The Kaplan-Meier method was used to calculate survival. A Cox proportional hazard model was constructed to evaluate the prognostic effect of the nutritional variables. Results: Unintentional weight loss (median: 11.3%; range: 2.6-34% of usual nonedematous body weight) was documented in 58 subjects (54.7%). Body mass index (BMI; in kg/m2) was ",

keywords = "Amyloidosis, Nutritional status, Outpatients, Prognosis, Survival, Weight loss",

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AU - Vagia, Christina

AU - Cameletti, Barbara

AU - Russo, Paola

AU - Lavatelli, Francesca

AU - Merlini, Giampaolo

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Nutritional status of outpatients with systemic immunoglobulin light-chain amyloidosis

Abstract

Keywords

ASJC Scopus subject areas

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