Abstract
Background: Maintenance of a good nutritional status is associated with prolonged survival in many chronic diseases. To date, the nutritional status of outpatients with immunoglobulin light-chain (AL) amyloidosis has not been evaluated. Objective: The aims of this study were to obtain information regarding the nutritional status of AL amyloidosis outpatients and to investigate its prognostic role. Design: One hundred six consecutive patients with histologically confirmed AL amyloidosis were enrolled. Anthropometric, biochemical, and clinical variables were measured. The Kaplan-Meier method was used to calculate survival. A Cox proportional hazard model was constructed to evaluate the prognostic effect of the nutritional variables. Results: Unintentional weight loss (median: 11.3%; range: 2.6-34% of usual nonedematous body weight) was documented in 58 subjects (54.7%). Body mass index (BMI; in kg/m2) was
Original language | English |
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Pages (from-to) | 350-354 |
Number of pages | 5 |
Journal | American Journal of Clinical Nutrition |
Volume | 83 |
Issue number | 2 |
Publication status | Published - Feb 1 2006 |
Keywords
- Amyloidosis
- Nutritional status
- Outpatients
- Prognosis
- Survival
- Weight loss
ASJC Scopus subject areas
- Medicine (miscellaneous)
- Food Science