Nutritional strategies in cancer patients. Oral supplementation and artificial nutrition

Francesco William Guglielmi, G. Leogrande, S. Mazzuoli, N. Regano, S. Fregnan, A. Guglielmi, G. Colucci, A. Francavilla

Research output: Contribution to journalArticlepeer-review


In the course of neoplastic disease, oncologic patients are frequently malnourished as a consequence of both cytokine hyperexpression due to cancer and the surgical or medical treatment they have undergone. The presence and stage of malnutrition depend on location, type and progression of cancer and often influence survival, efficacy of medical and radiation treatment, and also postsurgery morbidity and mortality. Research and clinical experience have shown to what extent artificial nutrition is able to prevent the negative effects of malnutrition on the course and prognosis of neoplastic disease and, most of all, on therapeutic efficacy. All of the above conditions show how important it is to adequately treat patients when they are suspected to be at risk of malnutrition. As a consequence, oncologists, nutritionists, and general practitioners should realize that the major targets of nutritional interventions in neoplastic patients are (a) to prevent further complications of their nutritional status, (b) to treat malnutrition, (c) to reduce postsurgery complications and mortality, and (d) to ensure a satisfying quality of life.

Original languageEnglish
Pages (from-to)101-112
Number of pages12
JournalNutritional Therapy and Metabolism
Issue number3
Publication statusPublished - Jul 2007


  • Anorexia-cachexia
  • Artificial nutrition
  • Cancer
  • Enteral nutrition
  • Oral supplementation
  • Parenteral nutrition

ASJC Scopus subject areas

  • Nutrition and Dietetics
  • Critical Care and Intensive Care Medicine


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