Obesità e rischio cardiovascolare in età pediatrica. Spunti di riflessione dallo studio ORIGIN

Translated title of the contribution: Obesity and cardiovascular risk in children

Research output: Contribution to journalArticle

Abstract

Prevalence of overweight and obesity in childhood has substantially increased worldwide in recent decades with children becoming obese at progressively younger ages. Obesity in children carries a wide range of serious complications, and contributes to an increased prevalence of cardiovascular risk factors such as hypertension, hypertrygliceridema, low high-density lipoprotein cholesterol (HDL), impaired glucose metabolism and early atherosclerotic changes not only in adulthood but since in very early pediatric age. In the ORIGIN study (Outcome Reduction with an Initial Glargine Intervention), cardiometabolic risk factors including fatty liver were already detectable in preschoolers at the onset of overweight/obesity despite short-term exposure to excess weight and fairly reduced insulin sensitivity. These facts together with the evidence that early cardiometabolic impairment reverts with lifestyle intervention in pediatric age, emphasize the need to start prevention of childhood obesity and screening of cardiometabolic co-morbities at the earliest stage with multidisciplinary strategies.

Original languageItalian
Pages (from-to)454-456
Number of pages3
JournalRecenti Progressi in Medicina
Volume105
Issue number12
Publication statusPublished - Dec 1 2014

Fingerprint

Pediatric Obesity
Obesity
Pediatrics
Fatty Liver
LDL Cholesterol
HDL Cholesterol
Insulin Resistance
Life Style
Outcome Assessment (Health Care)
Hypertension
Weights and Measures
Glucose

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Obesità e rischio cardiovascolare in età pediatrica. Spunti di riflessione dallo studio ORIGIN. / Shashaj, Blegina; Graziani, Maria Pia; Tozzi, Alberto Eugenio; Manco, Melania.

In: Recenti Progressi in Medicina, Vol. 105, No. 12, 01.12.2014, p. 454-456.

Research output: Contribution to journalArticle

@article{468d7a0272f84e719d61cb627698534a,
title = "Obesit{\`a} e rischio cardiovascolare in et{\`a} pediatrica. Spunti di riflessione dallo studio ORIGIN",
abstract = "Prevalence of overweight and obesity in childhood has substantially increased worldwide in recent decades with children becoming obese at progressively younger ages. Obesity in children carries a wide range of serious complications, and contributes to an increased prevalence of cardiovascular risk factors such as hypertension, hypertrygliceridema, low high-density lipoprotein cholesterol (HDL), impaired glucose metabolism and early atherosclerotic changes not only in adulthood but since in very early pediatric age. In the ORIGIN study (Outcome Reduction with an Initial Glargine Intervention), cardiometabolic risk factors including fatty liver were already detectable in preschoolers at the onset of overweight/obesity despite short-term exposure to excess weight and fairly reduced insulin sensitivity. These facts together with the evidence that early cardiometabolic impairment reverts with lifestyle intervention in pediatric age, emphasize the need to start prevention of childhood obesity and screening of cardiometabolic co-morbities at the earliest stage with multidisciplinary strategies.",
author = "Blegina Shashaj and Graziani, {Maria Pia} and Tozzi, {Alberto Eugenio} and Melania Manco",
year = "2014",
month = "12",
day = "1",
language = "Italian",
volume = "105",
pages = "454--456",
journal = "Recenti Progressi in Medicina",
issn = "0034-1193",
publisher = "Il Pensiero Scientifico Editore s.r.l.",
number = "12",

}

TY - JOUR

T1 - Obesità e rischio cardiovascolare in età pediatrica. Spunti di riflessione dallo studio ORIGIN

AU - Shashaj, Blegina

AU - Graziani, Maria Pia

AU - Tozzi, Alberto Eugenio

AU - Manco, Melania

PY - 2014/12/1

Y1 - 2014/12/1

N2 - Prevalence of overweight and obesity in childhood has substantially increased worldwide in recent decades with children becoming obese at progressively younger ages. Obesity in children carries a wide range of serious complications, and contributes to an increased prevalence of cardiovascular risk factors such as hypertension, hypertrygliceridema, low high-density lipoprotein cholesterol (HDL), impaired glucose metabolism and early atherosclerotic changes not only in adulthood but since in very early pediatric age. In the ORIGIN study (Outcome Reduction with an Initial Glargine Intervention), cardiometabolic risk factors including fatty liver were already detectable in preschoolers at the onset of overweight/obesity despite short-term exposure to excess weight and fairly reduced insulin sensitivity. These facts together with the evidence that early cardiometabolic impairment reverts with lifestyle intervention in pediatric age, emphasize the need to start prevention of childhood obesity and screening of cardiometabolic co-morbities at the earliest stage with multidisciplinary strategies.

AB - Prevalence of overweight and obesity in childhood has substantially increased worldwide in recent decades with children becoming obese at progressively younger ages. Obesity in children carries a wide range of serious complications, and contributes to an increased prevalence of cardiovascular risk factors such as hypertension, hypertrygliceridema, low high-density lipoprotein cholesterol (HDL), impaired glucose metabolism and early atherosclerotic changes not only in adulthood but since in very early pediatric age. In the ORIGIN study (Outcome Reduction with an Initial Glargine Intervention), cardiometabolic risk factors including fatty liver were already detectable in preschoolers at the onset of overweight/obesity despite short-term exposure to excess weight and fairly reduced insulin sensitivity. These facts together with the evidence that early cardiometabolic impairment reverts with lifestyle intervention in pediatric age, emphasize the need to start prevention of childhood obesity and screening of cardiometabolic co-morbities at the earliest stage with multidisciplinary strategies.

UR - http://www.scopus.com/inward/record.url?scp=84918829284&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84918829284&partnerID=8YFLogxK

M3 - Articolo

C2 - 25533232

AN - SCOPUS:84918829284

VL - 105

SP - 454

EP - 456

JO - Recenti Progressi in Medicina

JF - Recenti Progressi in Medicina

SN - 0034-1193

IS - 12

ER -