Occult choroidal neovascularization in adult-onset foveomacular vitelliform dystrophy

Stefano Da Pozzo, Maurizio Battaglia Parodi, Lisa Toto, Giuseppe Ravalico

Research output: Contribution to journalArticle

Abstract

Aims: To report 6 cases in which indocyanine green angiography (ICGA) failed to convert occult choroidal neovascularization (CNV) into well-defined CNV in adult-onset foveomacular vitelliform dystrophy (AOFVD). Methods: Patients with AOFVD observed from 1993 to 1999 were prospectively followed up. Whenever the development of CNV was suspected, ICGA was performed to detect the precise location and extension of CNV by means of the IMAGEnet System. Results: Six out of 51 patients (11.7%) developed CNV during the follow-up. The CNV was of the occult type, with an associated detachment of the pigment epithelium in 1 eye. On ICGA, a large hyperfluorescent lesion appeared after about 10 min, irregularly increasing with time, without a clear visualization of site and extension of CNV. Conclusions: In AOFVD, ICGA may fail to convert occult CNV into well-defined CNV, which is amenable to laser treatment, since hyperfluorescence caused by the probably vitelliform material binding to the ICG molecule and the CNV-induced hyperfluorescence cannot be angiographically distinguished from each other.

Original languageEnglish
Pages (from-to)412-414
Number of pages3
JournalOphthalmologica
Volume215
Issue number6
DOIs
Publication statusPublished - 2001

Keywords

  • Adult-onset foveomacular vitelliform dystrophy
  • Choroidal neovascularization
  • Indocyanine green angiography
  • Pigment epithelium detachment

ASJC Scopus subject areas

  • Ophthalmology

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