TY - JOUR
T1 - Occult large epiphyseal solitary plasmacytoma at multidetector row computer tomography detected by magnetic resonance imaging
AU - De Filippo, Massimo
AU - Pogliacomi, Francesco
AU - Albisinni, Ugo
AU - Quinto, Salvatore
AU - Bocchi, Carlo
AU - Sverzellati, Nicola
AU - Lipia, Stefano
AU - Zompatori, Maurizio
PY - 2008
Y1 - 2008
N2 - Myeloma or Kahler-Bozzolo disease represents around 1% of all malignant tumors and 10% of the haematological variety; it is a B-lymphocellular malignant neoplasia which originates from plasma cells that produce monoclonal immunoglobulin, infiltrating in and destroying the adjacent bone tissue. Myeloma may be distinguished at radiological imaging in four distinct types: single osseous lesions (solitary plasmacytoma), diffused skeletal effects (myelomatosis), diffused osteopenia and sclerosing myeloma. It is known that initial osteolysis may not be shown through radiographic examination or CT; the lysis only becomes evident when there is a bone loss of over 50%, usually in the presence of a =/> 0,5 cm focal lesion. We present here the clinical-radiological aspects of a solitary bone plasmacitoma (SBP) of the knee of a 35 year old male which was not evidenced at radiological examination or CT but was evident as a 3 cm focal alteration at MR. The lesion was confirmed by PET and the histological diagnosis was performed by a CT guided bioptic sample. (www.actabiomedica.it).
AB - Myeloma or Kahler-Bozzolo disease represents around 1% of all malignant tumors and 10% of the haematological variety; it is a B-lymphocellular malignant neoplasia which originates from plasma cells that produce monoclonal immunoglobulin, infiltrating in and destroying the adjacent bone tissue. Myeloma may be distinguished at radiological imaging in four distinct types: single osseous lesions (solitary plasmacytoma), diffused skeletal effects (myelomatosis), diffused osteopenia and sclerosing myeloma. It is known that initial osteolysis may not be shown through radiographic examination or CT; the lysis only becomes evident when there is a bone loss of over 50%, usually in the presence of a =/> 0,5 cm focal lesion. We present here the clinical-radiological aspects of a solitary bone plasmacitoma (SBP) of the knee of a 35 year old male which was not evidenced at radiological examination or CT but was evident as a 3 cm focal alteration at MR. The lesion was confirmed by PET and the histological diagnosis was performed by a CT guided bioptic sample. (www.actabiomedica.it).
KW - Epiphyseal solitary plasmacytoma
KW - Knee
KW - MDCT
KW - MRI
KW - PET
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M3 - Article
C2 - 19260386
AN - SCOPUS:63049106960
VL - 79
SP - 240
EP - 245
JO - Acta Biomedica de l'Ateneo Parmense
JF - Acta Biomedica de l'Ateneo Parmense
SN - 0392-4203
IS - 3
ER -