Linfonodi mediastinici occulti nel NCCLC: Ripercussioni della falsa negatività PET/TC sulla stadiazione e sulla terapia. Caso clinico e rassegna critica

L. Trodella; F. Salvati; M. Martelli; P. Mattia; P. Graziano; E. Ippolito

Linfonodi mediastinici occulti nel NCCLC: Ripercussioni della falsa negatività PET/TC sulla stadiazione e sulla terapia. Caso clinico e rassegna critica

Translated title of the contribution: Occult mediastinal node involvement in non-small cell lung cancer after negative uptake on PET/CT: Ripples through staging and therapy. Case report and critical review

L. Trodella, F. Salvati, M. Martelli, P. Mattia, P. Graziano, E. Ippolito

IRCCS Casa Sollievo della Sofferenza

Research output: Contribution to journal › Article › peer-review

Abstract

A 78-years old man, heavy smoker, with a persistent and hacking cough, was diagnosed with an adenocarcinoma of upper lobe of left lung. Clinical stage was defi ned as cT2N0M0 also on the basis of a negative 18FDG-PET/TC. After lobectomy, pathological stage resulted, on the contrary, pT2N2M0. Because the considerable incidence of preoperative false negative uptakes of PET/TC for involvement of mediastinal lymph nodes, this case report is highlighted as emblematic, particularly in relation to post-operative treatment of early stage NSCLC.

Translated title of the contribution	Occult mediastinal node involvement in non-small cell lung cancer after negative uptake on PET/CT: Ripples through staging and therapy. Case report and critical review
Original language	Italian
Pages (from-to)	559-561
Number of pages	3
Journal	Clinica Terapeutica
Volume	162
Issue number	6
Publication status	Published - 2011

ASJC Scopus subject areas

Medicine(all)

Cite this

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title = "Linfonodi mediastinici occulti nel NCCLC: Ripercussioni della falsa negativit{\`a} PET/TC sulla stadiazione e sulla terapia. Caso clinico e rassegna critica",

abstract = "A 78-years old man, heavy smoker, with a persistent and hacking cough, was diagnosed with an adenocarcinoma of upper lobe of left lung. Clinical stage was defi ned as cT2N0M0 also on the basis of a negative 18FDG-PET/TC. After lobectomy, pathological stage resulted, on the contrary, pT2N2M0. Because the considerable incidence of preoperative false negative uptakes of PET/TC for involvement of mediastinal lymph nodes, this case report is highlighted as emblematic, particularly in relation to post-operative treatment of early stage NSCLC.",

keywords = "Lung cancer, Mediastinal occult metastases, PET/TC, Staging, Therapy",

author = "L. Trodella and F. Salvati and M. Martelli and P. Mattia and P. Graziano and E. Ippolito",

year = "2011",

language = "Italian",

volume = "162",

pages = "559--561",

journal = "Clinica Terapeutica",

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T1 - Linfonodi mediastinici occulti nel NCCLC

T2 - Ripercussioni della falsa negatività PET/TC sulla stadiazione e sulla terapia. Caso clinico e rassegna critica

AU - Trodella, L.

AU - Salvati, F.

AU - Martelli, M.

AU - Mattia, P.

AU - Graziano, P.

AU - Ippolito, E.

PY - 2011

Y1 - 2011

N2 - A 78-years old man, heavy smoker, with a persistent and hacking cough, was diagnosed with an adenocarcinoma of upper lobe of left lung. Clinical stage was defi ned as cT2N0M0 also on the basis of a negative 18FDG-PET/TC. After lobectomy, pathological stage resulted, on the contrary, pT2N2M0. Because the considerable incidence of preoperative false negative uptakes of PET/TC for involvement of mediastinal lymph nodes, this case report is highlighted as emblematic, particularly in relation to post-operative treatment of early stage NSCLC.

AB - A 78-years old man, heavy smoker, with a persistent and hacking cough, was diagnosed with an adenocarcinoma of upper lobe of left lung. Clinical stage was defi ned as cT2N0M0 also on the basis of a negative 18FDG-PET/TC. After lobectomy, pathological stage resulted, on the contrary, pT2N2M0. Because the considerable incidence of preoperative false negative uptakes of PET/TC for involvement of mediastinal lymph nodes, this case report is highlighted as emblematic, particularly in relation to post-operative treatment of early stage NSCLC.

KW - Lung cancer

KW - Mediastinal occult metastases

KW - PET/TC

KW - Staging

KW - Therapy

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AN - SCOPUS:84858411504

VL - 162

SP - 559

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JO - Clinica Terapeutica

JF - Clinica Terapeutica

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Linfonodi mediastinici occulti nel NCCLC: Ripercussioni della falsa negatività PET/TC sulla stadiazione e sulla terapia. Caso clinico e rassegna critica

Abstract

ASJC Scopus subject areas

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