Abstract
Objective: To estimate risks for laryngeal/hypopharyngeal cancer associated with occupational titles and industrial activities. Methods: A multicentre population-based case-control study was conducted in the early 1980s in six southern European areas. Analyses included 1010 male cases and 2176 controls. Odds ratios (ORs) (adjusted for age, study area, tobacco consumption, and alcohol consumption) were estimated for 156 occupations and 70 industrial activities. Results: An excess risk has been confirmed for categories of construction workers, potters (OR: 5.91, 95% confidence intervals 1.46-24.0), butchers (2.53, 1.22-5.22), barbers (2.33, 1.00-5.40), laborers not otherwise specified (1.52, 1.12-2.06), as well as for men who had been employed in railway transport (1.52, 0.97-2.39), shipbuilding (2.05, 0.89-4.94), and hotels (2.06, 0.89-4.75). An association was also found for shoe finishers (3.23, 0.75-13.9), loggers (2.07, 0.87-4.90), and some groups of metal workers. ORs for loggers, butchers, railway transport workers, laborers, and reinforced concreters increased with duration of employment. The suggestion of a risk for machine operators among woodworkers (3.10, 0.92-10.5) conflicts with previous findings. No significant excess of risk was found for categories previously reported to be associated with laryngeal and hypopharyngeal cancer, such as drivers, mechanics, welders, machinists, and painters. Conclusions: The present study provides additional evidence to the hypothesis of a risk of cancer of the larynx/hypopharynx for workers engaged in jobs in the construction, metal, textile, ceramic, and food industries and in railway transport. Loggers were also found at risk; a previously unreported finding.
| Original language | English |
|---|---|
| Pages (from-to) | 203-212 |
| Number of pages | 10 |
| Journal | Cancer Causes and Control |
| Volume | 14 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - Apr 2003 |
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Keywords
- Barbers
- Butchers
- Construction workers
- Hypopharynx cancer
- Larynx cancer
- Occupation
- Potters
ASJC Scopus subject areas
- Oncology
- Epidemiology
- Cancer Research
Cite this
Occupation and larynx and hypopharynx cancer : An international case-control study in France, Italy, Spain, and Switzerland. / Boffetta, Paolo; Richiardi, Lorenzo; Berrino, Franco; Estève, Jacques; Pisani, Paola; Crosignani, Paolo; Raymond, Luc; Zubiri, Lourdes; Del Moral, Angel; Lehmann, Willy; Donato, Francesco; Terracini, Benedetto; Tuyns, Albert; Merletti, Franco.
In: Cancer Causes and Control, Vol. 14, No. 3, 04.2003, p. 203-212.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Occupation and larynx and hypopharynx cancer
T2 - An international case-control study in France, Italy, Spain, and Switzerland
AU - Boffetta, Paolo
AU - Richiardi, Lorenzo
AU - Berrino, Franco
AU - Estève, Jacques
AU - Pisani, Paola
AU - Crosignani, Paolo
AU - Raymond, Luc
AU - Zubiri, Lourdes
AU - Del Moral, Angel
AU - Lehmann, Willy
AU - Donato, Francesco
AU - Terracini, Benedetto
AU - Tuyns, Albert
AU - Merletti, Franco
PY - 2003/4
Y1 - 2003/4
N2 - Objective: To estimate risks for laryngeal/hypopharyngeal cancer associated with occupational titles and industrial activities. Methods: A multicentre population-based case-control study was conducted in the early 1980s in six southern European areas. Analyses included 1010 male cases and 2176 controls. Odds ratios (ORs) (adjusted for age, study area, tobacco consumption, and alcohol consumption) were estimated for 156 occupations and 70 industrial activities. Results: An excess risk has been confirmed for categories of construction workers, potters (OR: 5.91, 95% confidence intervals 1.46-24.0), butchers (2.53, 1.22-5.22), barbers (2.33, 1.00-5.40), laborers not otherwise specified (1.52, 1.12-2.06), as well as for men who had been employed in railway transport (1.52, 0.97-2.39), shipbuilding (2.05, 0.89-4.94), and hotels (2.06, 0.89-4.75). An association was also found for shoe finishers (3.23, 0.75-13.9), loggers (2.07, 0.87-4.90), and some groups of metal workers. ORs for loggers, butchers, railway transport workers, laborers, and reinforced concreters increased with duration of employment. The suggestion of a risk for machine operators among woodworkers (3.10, 0.92-10.5) conflicts with previous findings. No significant excess of risk was found for categories previously reported to be associated with laryngeal and hypopharyngeal cancer, such as drivers, mechanics, welders, machinists, and painters. Conclusions: The present study provides additional evidence to the hypothesis of a risk of cancer of the larynx/hypopharynx for workers engaged in jobs in the construction, metal, textile, ceramic, and food industries and in railway transport. Loggers were also found at risk; a previously unreported finding.
AB - Objective: To estimate risks for laryngeal/hypopharyngeal cancer associated with occupational titles and industrial activities. Methods: A multicentre population-based case-control study was conducted in the early 1980s in six southern European areas. Analyses included 1010 male cases and 2176 controls. Odds ratios (ORs) (adjusted for age, study area, tobacco consumption, and alcohol consumption) were estimated for 156 occupations and 70 industrial activities. Results: An excess risk has been confirmed for categories of construction workers, potters (OR: 5.91, 95% confidence intervals 1.46-24.0), butchers (2.53, 1.22-5.22), barbers (2.33, 1.00-5.40), laborers not otherwise specified (1.52, 1.12-2.06), as well as for men who had been employed in railway transport (1.52, 0.97-2.39), shipbuilding (2.05, 0.89-4.94), and hotels (2.06, 0.89-4.75). An association was also found for shoe finishers (3.23, 0.75-13.9), loggers (2.07, 0.87-4.90), and some groups of metal workers. ORs for loggers, butchers, railway transport workers, laborers, and reinforced concreters increased with duration of employment. The suggestion of a risk for machine operators among woodworkers (3.10, 0.92-10.5) conflicts with previous findings. No significant excess of risk was found for categories previously reported to be associated with laryngeal and hypopharyngeal cancer, such as drivers, mechanics, welders, machinists, and painters. Conclusions: The present study provides additional evidence to the hypothesis of a risk of cancer of the larynx/hypopharynx for workers engaged in jobs in the construction, metal, textile, ceramic, and food industries and in railway transport. Loggers were also found at risk; a previously unreported finding.
KW - Barbers
KW - Butchers
KW - Construction workers
KW - Hypopharynx cancer
KW - Larynx cancer
KW - Occupation
KW - Potters
UR - http://www.scopus.com/inward/record.url?scp=0038237365&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0038237365&partnerID=8YFLogxK
U2 - 10.1023/A:1023699717598
DO - 10.1023/A:1023699717598
M3 - Article
C2 - 12814199
AN - SCOPUS:0038237365
VL - 14
SP - 203
EP - 212
JO - Cancer Causes and Control
JF - Cancer Causes and Control
SN - 0957-5243
IS - 3
ER -