Occupational and leisure-time physical activity and the risk of colorectal cancer

Facio Levi, C. Pasche, F. Lucchini, A. Tavani, C. La Vecchia

Research output: Contribution to journalArticle

Abstract

The relation between various measures of physical activity and colorectal cancer risk was considered in a case-control study conducted between 1992 and 1997 in the Swiss canton of Vaud. Cases were 223 patients (142 men, 81 women) below age 75, with colon (n = 119) or rectal (n = 104) cancer; controls were 491 patients (211 men, 280 women) admitted to hospital for acute, non-neoplastic conditions. Compared with the lowest level of physical activity at age 30-39 years, the odds ratios (OR) of colorectal cancer for the highest level were 0.44 (95% confidence interval, CI, 0.26- 0.73) for occupational and 0.53 (95% CI 0.33-0.86) for leisure-time activity. An inverse association was also observed for physical activity at age 15-19 and 50-59 years. The inverse relation between physical activity and colorectal cancer was observed across strata of sex, age, education, body mass index and alcohol drinking; was somewhat stronger in subjects reporting high total energy, and low vegetable and fibre intakes; and was observed across various colon subsites and rectum. In terms of population attributable risk, increasing physical activity would avoid one-fifth to one-third of incident colorectal cancer cases.

Original languageEnglish
Pages (from-to)487-493
Number of pages7
JournalEuropean Journal of Cancer Prevention
Volume8
Issue number6
Publication statusPublished - 1999

Fingerprint

Leisure Activities
Colorectal Neoplasms
Exercise
Colon
Sex Education
Rectum
Alcohol Drinking
Vegetables
Case-Control Studies
Body Mass Index
Odds Ratio
Confidence Intervals
Population
Neoplasms

Keywords

  • Case-control study
  • Colon cancer
  • Epidemiology
  • Physical activity
  • Rectal cancer
  • Risk

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Levi, F., Pasche, C., Lucchini, F., Tavani, A., & La Vecchia, C. (1999). Occupational and leisure-time physical activity and the risk of colorectal cancer. European Journal of Cancer Prevention, 8(6), 487-493.

Occupational and leisure-time physical activity and the risk of colorectal cancer. / Levi, Facio; Pasche, C.; Lucchini, F.; Tavani, A.; La Vecchia, C.

In: European Journal of Cancer Prevention, Vol. 8, No. 6, 1999, p. 487-493.

Research output: Contribution to journalArticle

Levi, F, Pasche, C, Lucchini, F, Tavani, A & La Vecchia, C 1999, 'Occupational and leisure-time physical activity and the risk of colorectal cancer', European Journal of Cancer Prevention, vol. 8, no. 6, pp. 487-493.
Levi, Facio ; Pasche, C. ; Lucchini, F. ; Tavani, A. ; La Vecchia, C. / Occupational and leisure-time physical activity and the risk of colorectal cancer. In: European Journal of Cancer Prevention. 1999 ; Vol. 8, No. 6. pp. 487-493.
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