Occupational and leisure-time physical activity and the risk of colorectal cancer

Facio Levi, C. Pasche, F. Lucchini, A. Tavani, C. La Vecchia

Research output: Contribution to journalArticle

Abstract

The relation between various measures of physical activity and colorectal cancer risk was considered in a case-control study conducted between 1992 and 1997 in the Swiss canton of Vaud. Cases were 223 patients (142 men, 81 women) below age 75, with colon (n = 119) or rectal (n = 104) cancer; controls were 491 patients (211 men, 280 women) admitted to hospital for acute, non-neoplastic conditions. Compared with the lowest level of physical activity at age 30-39 years, the odds ratios (OR) of colorectal cancer for the highest level were 0.44 (95% confidence interval, CI, 0.26- 0.73) for occupational and 0.53 (95% CI 0.33-0.86) for leisure-time activity. An inverse association was also observed for physical activity at age 15-19 and 50-59 years. The inverse relation between physical activity and colorectal cancer was observed across strata of sex, age, education, body mass index and alcohol drinking; was somewhat stronger in subjects reporting high total energy, and low vegetable and fibre intakes; and was observed across various colon subsites and rectum. In terms of population attributable risk, increasing physical activity would avoid one-fifth to one-third of incident colorectal cancer cases.

Original languageEnglish
Pages (from-to)487-493
Number of pages7
JournalEuropean Journal of Cancer Prevention
Volume8
Issue number6
Publication statusPublished - 1999

Keywords

  • Case-control study
  • Colon cancer
  • Epidemiology
  • Physical activity
  • Rectal cancer
  • Risk

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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  • Cite this

    Levi, F., Pasche, C., Lucchini, F., Tavani, A., & La Vecchia, C. (1999). Occupational and leisure-time physical activity and the risk of colorectal cancer. European Journal of Cancer Prevention, 8(6), 487-493.