Occupational asthma due to styrene: Two case reports

Gianna Moscato, Giampiero Biscaldi, Danilo Cottica, Franco Pugliese, Stefano Candura, Francesco Candura

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Two cases of occupational asthma due to styrene are described. The subjects complained of cough, breathlessness, and symptoms of asthma when coming into contact with styrene; in patient 1 the respiratory reaction was followed by a late cutaneous rash. The symptoms disappeared when the subjects were away from work on weekends or holidays. In both cases, inhalation challenge with styrene produced an immediate bronchospastic reaction which was followed by a late cutaneous rash in patient 1. Prior administration of disodium cromogly-cate (40 mg from a spinhaler) prevented the respiratory reactions completely, but failed to prevent the late skin response in case 1. Styrene removal was followed by complete disappearance of the symptoms. We conclude that styrene can be a primary cause of occupational asthma.

Original languageEnglish
Pages (from-to)957-960
Number of pages4
JournalJournal of Occupational Medicine
Issue number12
Publication statusPublished - 1987

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

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    Moscato, G., Biscaldi, G., Cottica, D., Pugliese, F., Candura, S., & Candura, F. (1987). Occupational asthma due to styrene: Two case reports. Journal of Occupational Medicine, 29(12), 957-960.