Occupational dermatitis in bakers: A clue for atopic contact dermatitis

P. D. Pigatto, M. M. Polenghi, G. F. Altomare

Research output: Contribution to journalArticle


6 patients are described who developed contact dermatitis after cereal contact on atopic skin for periods of 2 to 20 years. 2 patients were wheat flour patch-test-positive. They had punch biopsies taken for standard histological and immunohistochemical investigation by labeling with monoclonal antibodies, anti-DR and anti-IgE. Sections showed features of contact dermatitis. There were many dendritic cells located perivascularly in the papilla and in the epidermidis, intensely positive for monoclonal anti-IgE antibody. In control atopic subjects, there were a few perivascular IgE positive cells, probably mastocytes. This study shows that there may be a relationship between some allergens and atopic eczema in patients exposed to them in the course of their work. In some cases, there was a true allergic contact dermatitis, seen through the clinical and histological characteristics, and the results of immunohistochemical study.

Original languageEnglish
Pages (from-to)263-271
Number of pages9
JournalContact Dermatitis
Issue number5
Publication statusPublished - 1987

ASJC Scopus subject areas

  • Immunology
  • Dermatology
  • Toxicology

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