Occupational, environmental, and life-style factors associated with the risk of hematolymphopoietic malignancies in women

Lucia Miligi, A. Seniori Costantini, P. Crosignani, A. Fontana, G. Masala, O. Nanni, V. Ramazzotti, S. Rodella, E. Stagnaro, R. Tumino, C. Viganò, C. Vindigni, P. Vineis

Research output: Contribution to journalArticle

Abstract

Background: The etiology of lymphomas, leukemias, and multiple myeloma is still largely unknown. The known risk factors (ionizing radiation, solvent exposure, pesticide exposure, immunosuppression) explain only a small proportion of the cases that occur. Methods: We conducted a multicenter population-based case-control study on hematolymphopoietic malignancies in Italy and interviewed 2,011 women (1,183 cases and 828 controls). Results: There was a suggestion of a positive association between smoking and the risk of non-Hodgkin's lymphoma + chronic lymphocytic leukemia. A slight increased risk of leukemias was observed among women using permanent hair dye. Housewives were at increased risk for leukemia and multiple myeloma. The risk of non-Hodgkin's lymphomas + chronic lymphocytic leukemia, leukemias, multiple myeloma, and Hodgkin's disease increased among women employed as hairdressers and textile workers. Teachers were at increased risk for non- Hodgkin's lymphomas + chronic lymphocytic leukemia, leukemias, and Hodgkin's disease. Conclusions: These results confirm previous associations and may provide additional clues to some determinants of hematolymphopoietic malignancies in women.

Original languageEnglish
Pages (from-to)60-69
Number of pages10
JournalAmerican Journal of Industrial Medicine
Volume36
Issue number1
DOIs
Publication statusPublished - 1999

Keywords

  • Hair dyes
  • Housewives
  • Leukemias
  • Lymphomas
  • Multiple myeloma
  • Occupations

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

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    Miligi, L., Seniori Costantini, A., Crosignani, P., Fontana, A., Masala, G., Nanni, O., Ramazzotti, V., Rodella, S., Stagnaro, E., Tumino, R., Viganò, C., Vindigni, C., & Vineis, P. (1999). Occupational, environmental, and life-style factors associated with the risk of hematolymphopoietic malignancies in women. American Journal of Industrial Medicine, 36(1), 60-69. https://doi.org/10.1002/(SICI)1097-0274(199907)36:1<60::AID-AJIM9>3.0.CO;2-Z