Esposizione professionalle a distruttori endocrini: Stato dell'arte

Translated title of the contribution: Occupational exposure to endocrine disrupters chemicals: State of the art

Bruno Papaleo, L. Caporossi, M. De Rosa, L. Chiovato, M. Ferrari, M. Imbriani, S. Signorini, A. Pera

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Research into how exposure to "endocrine disrupters chemicals" affects human health is attracting increasing attention among European and international scientists since these contaminants are so widespread in the home and work environment and can have far-reaching effects on mental and physical health. Here we draw a general picture of studies to date on specific occupational exposures to single chemicals such as biphenol A, styrene, etc., or homogeneous groups such as pesticides, metals, dioxins, phthalates and others. Although the exposure occurs in different ways, the toxic mechanisms of action vary widely, and it is hard to establish precisely the conditions of occupational exposure, significant correlations are nevertheless evident between the potential dose and its effects and further studies are certainty needed. There is still much debate on the epidemiological methods employed, which may overestimate exposure. The "measure" or at least an accurate description of exposure conditions is critical to the whole question and attempts to ensure this involve standardized procedures and statistical tests as the basis for a protocol for assessing the risk of occupational exposure. Investigations to date have focused on the effects on the reproductive system, in males in particular. However, considering the broad range of equilibria and systems on which endocrine destructive compounds can act, the international scientific community needs to persist in its efforts to develop methods for checking the effects on other endocrine organs - particularly the thyroid gland - and on the immune and neurological systems.

Original languageItalian
Pages (from-to)171-179
Number of pages9
JournalGiornale Italiano di Medicina del Lavoro ed Ergonomia
Volume26
Issue number3
Publication statusPublished - Sep 2004

Fingerprint

Occupational Exposure
Epidemiologic Methods
Toxic Actions
Styrene
Dioxins
Pesticides
Immune System
Mental Health
Thyroid Gland
Metals
Health
Research

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Rehabilitation

Cite this

Esposizione professionalle a distruttori endocrini : Stato dell'arte. / Papaleo, Bruno; Caporossi, L.; De Rosa, M.; Chiovato, L.; Ferrari, M.; Imbriani, M.; Signorini, S.; Pera, A.

In: Giornale Italiano di Medicina del Lavoro ed Ergonomia, Vol. 26, No. 3, 09.2004, p. 171-179.

Research output: Contribution to journalArticle

Papaleo, B, Caporossi, L, De Rosa, M, Chiovato, L, Ferrari, M, Imbriani, M, Signorini, S & Pera, A 2004, 'Esposizione professionalle a distruttori endocrini: Stato dell'arte', Giornale Italiano di Medicina del Lavoro ed Ergonomia, vol. 26, no. 3, pp. 171-179.
Papaleo, Bruno ; Caporossi, L. ; De Rosa, M. ; Chiovato, L. ; Ferrari, M. ; Imbriani, M. ; Signorini, S. ; Pera, A. / Esposizione professionalle a distruttori endocrini : Stato dell'arte. In: Giornale Italiano di Medicina del Lavoro ed Ergonomia. 2004 ; Vol. 26, No. 3. pp. 171-179.
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