Occupational HIV infection in a research laboratory with unknown mode of transmission

a case report

Alessandro Soria, Claudia Alteri, Gabriella Scarlatti, Ada Bertoli, Monica Tolazzi, Emanuela Balestra, Maria Concetta Bellocchi, Fabio Continenza, Luca Carioti, Mara Biasin, Daria Trabattoni, Alessandra Bandera, Francesca Ceccherini-Silberstein, Carlo Federico Perno, Andrea Gori

Research output: Contribution to journalArticle

Abstract

A lab-worker was infected with HIV-1 in a biosafety level-2 of containment, without any apparent breach. Through full-genome sequencing and phylogenetic analyses, we could identify the source of infection in a replication-competent clone, unknowingly contaminating a safe experiment. Mode of transmission remains unclear. Caution is warranted when handling HIV-derived constructs.

Original languageEnglish
JournalClinical Infectious Diseases
DOIs
Publication statusE-pub ahead of print - Dec 28 2016

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HIV Infections
HIV-1
Clone Cells
HIV
Genome
Infection
Research

Keywords

  • Journal Article

Cite this

Occupational HIV infection in a research laboratory with unknown mode of transmission : a case report. / Soria, Alessandro; Alteri, Claudia; Scarlatti, Gabriella; Bertoli, Ada; Tolazzi, Monica; Balestra, Emanuela; Bellocchi, Maria Concetta; Continenza, Fabio; Carioti, Luca; Biasin, Mara; Trabattoni, Daria; Bandera, Alessandra; Ceccherini-Silberstein, Francesca; Perno, Carlo Federico; Gori, Andrea.

In: Clinical Infectious Diseases, 28.12.2016.

Research output: Contribution to journalArticle

Soria, A, Alteri, C, Scarlatti, G, Bertoli, A, Tolazzi, M, Balestra, E, Bellocchi, MC, Continenza, F, Carioti, L, Biasin, M, Trabattoni, D, Bandera, A, Ceccherini-Silberstein, F, Perno, CF & Gori, A 2016, 'Occupational HIV infection in a research laboratory with unknown mode of transmission: a case report', Clinical Infectious Diseases. https://doi.org/10.1093/cid/ciw851
Soria, Alessandro ; Alteri, Claudia ; Scarlatti, Gabriella ; Bertoli, Ada ; Tolazzi, Monica ; Balestra, Emanuela ; Bellocchi, Maria Concetta ; Continenza, Fabio ; Carioti, Luca ; Biasin, Mara ; Trabattoni, Daria ; Bandera, Alessandra ; Ceccherini-Silberstein, Francesca ; Perno, Carlo Federico ; Gori, Andrea. / Occupational HIV infection in a research laboratory with unknown mode of transmission : a case report. In: Clinical Infectious Diseases. 2016.
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AU - Scarlatti, Gabriella

AU - Bertoli, Ada

AU - Tolazzi, Monica

AU - Balestra, Emanuela

AU - Bellocchi, Maria Concetta

AU - Continenza, Fabio

AU - Carioti, Luca

AU - Biasin, Mara

AU - Trabattoni, Daria

AU - Bandera, Alessandra

AU - Ceccherini-Silberstein, Francesca

AU - Perno, Carlo Federico

AU - Gori, Andrea

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