Occupational HIV infection in a research laboratory with unknown mode of transmission: A case report

A Soria, C Alteri, G Scarlatti, Ada Bertoli, M Tolazzi, Emanuela Balestra, MC Bellocchi, F Continenza, L Carioti, Mara Biasin, D Trabattoni, A Bandera, Francesca Ceccherini-Silberstein, CF Perno, A Gori

Research output: Contribution to journalArticle

Abstract

A lab-worker was infected with HIV-1 in a biosafety level-2 of containment, without any apparent breach. Through full-genome sequencing and phylogenetic analyses, we could identify the source of infection in a replication-competent clone, unknowingly contaminating a safe experiment. Mode of transmission remains unclear. Caution is warranted when handling HIV-derived constructs. © The Author 2016.
Original languageEnglish
Pages (from-to)3-15
Number of pages13
JournalClinical Infectious Diseases
Volume64
Issue number6
DOIs
Publication statusPublished - 2017

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    Soria, A., Alteri, C., Scarlatti, G., Bertoli, A., Tolazzi, M., Balestra, E., Bellocchi, MC., Continenza, F., Carioti, L., Biasin, M., Trabattoni, D., Bandera, A., Ceccherini-Silberstein, F., Perno, CF., & Gori, A. (2017). Occupational HIV infection in a research laboratory with unknown mode of transmission: A case report. Clinical Infectious Diseases, 64(6), 3-15. https://doi.org/10.1093/cid/ciw851