Translated title of the contribution: Occuptional polyneuropathy due to cyclohexane

G. Franco, A. Moglia, S. Ghittori

Research output: Contribution to journalArticlepeer-review


A description is presented of a clinical case of toxic neuropathy in an individual employed at painting automobile chassis. Polyneuritic involvement was confirmed by the neurophysiological data (increased width and duration and presence of motor unit potential above 15%, deficit in gathering maximum force, maximum motor conduction velocity reduced at the bilateral sciatic-popliteal and radial level, sensitive orthodromic conduction velocity reduced at the bilateral peroneal level). A study of the working environment to detect the presence of any possible neurotoxic agent was done by means of gas chromatographic analysis of the air, determining both peak and mean exposure levels. The presence of solvents was revealed (cyclohexane, acetone, toluene, xylene, isobutyl alcohol) in concentrations below permissible limits. Chromatographic analysis of the solvents gave a relative high percentage of cyclohexane compared with toluene and isobutyl alcohol, but the presence of tricresyl phosphate (using gas chromatography) and lead (using atomic absorption spectrophotometry) was ruled out. Considering the fact that after the occurrence of this case of polyneuropathy a number of technical measures were taken to improve the environmental hygiene conditions of the place of work, it could be deduced that in the past there was a much higher degree of pollution from solvents and in particular cyclohexane. Also on the basis of the experimental data in the literature, the etiology of the sensory-motor polyneuropathy described may be attributed to the toxic action of cyclohexane.

Translated title of the contributionOccuptional polyneuropathy due to cyclohexane
Original languageItalian
Pages (from-to)118-124
Number of pages7
JournalMedicina del Lavoro
Issue number2
Publication statusPublished - 1979

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health


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