Ochronotic arthropathy: Rapid destructive hip osteoarthritis associated with metabolic disease

T. Corrà, M. Zaccala, M. Galante

Research output: Contribution to journalArticlepeer-review

Abstract

Ochronosis is a musculoskeletal manifestation of alkaptonuria, an inherited metabolic disorder associated with various systemic abnormalities related to the deposition of homogentisic acid pigment in connective tissues. This report describes a 58-year-old woman with ochronotic arthropathy who, in addition to the typical clinical features of the disorder, presented with rapidly progressive hip osteoarthritis. The destruction of the joint architecture and the severe functional impairment necessitated a total hip replacement which resulted in a satisfactory outcome.

Original languageEnglish
Pages (from-to)474-477
Number of pages4
JournalClinical Rheumatology
Volume14
Issue number4
DOIs
Publication statusPublished - Jul 1995

Keywords

  • Alkaptonuria
  • Homogentisic Acid
  • Ochronosis
  • Ochronotic Arthropathy
  • Rapid Destructive Hip Osteoarthritis

ASJC Scopus subject areas

  • Rheumatology
  • Immunology

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