Abstract
| Original language | English |
|---|---|
| Pages (from-to) | 986-990 |
| Number of pages | 5 |
| Journal | Inflammatory Bowel Diseases |
| Volume | 23 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - Jun 1 2017 |
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Keywords
- children
- extraintestinal manifestations
- inflammatory bowel disease
- uveitis
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Ocular Involvement in Children with Inflammatory Bowel Disease. / Naviglio, Samuele; Parentin, Fulvio; Nider, Silvia; Rassu, Nicolò; Martelossi, Stefano; Ventura, Alessandro; Ventura, Alessandro.
In: Inflammatory Bowel Diseases, Vol. 23, No. 6, 01.06.2017, p. 986-990.Research output: Contribution to journal › Review article
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TY - JOUR
T1 - Ocular Involvement in Children with Inflammatory Bowel Disease
AU - Naviglio, Samuele
AU - Parentin, Fulvio
AU - Nider, Silvia
AU - Rassu, Nicolò
AU - Martelossi, Stefano
AU - Ventura, Alessandro
AU - Ventura, Alessandro
PY - 2017/6/1
Y1 - 2017/6/1
N2 - Copyright © 2017 Crohn's & Colitis Foundation. Background: Data on ocular manifestations of inflammatory bowel disease (IBD) in children are limited. Some authors have reported a high prevalence of asymptomatic uveitis, yet the significance of these observations is unknown and there are no recommendations on which ophthalmologic follow-up should be offered. Methods: Children with IBD seen at a single referral center for pediatric gastroenterology were offered ophthalmologic evaluation as part of routine care for their disease. Ophthalmologic evaluation included review of ocular history as well as slit-lamp and fundoscopic examination. Medical records were also reviewed for previous ophthalmologic diagnoses or complaints. Results: Data from 94 children were included (52 boys; median age 13.4 yr). Forty-six patients had a diagnosis of Crohn's disease, 46 ulcerative colitis, and 2 IBD unclassified. Intestinal disease was in clinical remission in 70% of the patients; fecal calprotectin was elevated in 64%. One patient with Crohn's disease had a previous diagnosis of clinically manifest uveitis (overall uveitis prevalence: 1.06%; incidence rate: 0.3 per 100 patient-years). This patient was also the only one who was found to have asymptomatic uveitis at slit-lamp examination. A second patient had posterior subcapsular cataract associated with corticosteroid treatment. No signs of intraocular complications from previous unrecognized uveitis were observed in any patient. Conclusions: Children with IBD may have asymptomatic uveitis, yet its prevalence seems lower than previously reported, and it was not found in children without a previous diagnosis of clinically manifest uveitis. No ocular complications from prior unrecognized uveitis were observed.
AB - Copyright © 2017 Crohn's & Colitis Foundation. Background: Data on ocular manifestations of inflammatory bowel disease (IBD) in children are limited. Some authors have reported a high prevalence of asymptomatic uveitis, yet the significance of these observations is unknown and there are no recommendations on which ophthalmologic follow-up should be offered. Methods: Children with IBD seen at a single referral center for pediatric gastroenterology were offered ophthalmologic evaluation as part of routine care for their disease. Ophthalmologic evaluation included review of ocular history as well as slit-lamp and fundoscopic examination. Medical records were also reviewed for previous ophthalmologic diagnoses or complaints. Results: Data from 94 children were included (52 boys; median age 13.4 yr). Forty-six patients had a diagnosis of Crohn's disease, 46 ulcerative colitis, and 2 IBD unclassified. Intestinal disease was in clinical remission in 70% of the patients; fecal calprotectin was elevated in 64%. One patient with Crohn's disease had a previous diagnosis of clinically manifest uveitis (overall uveitis prevalence: 1.06%; incidence rate: 0.3 per 100 patient-years). This patient was also the only one who was found to have asymptomatic uveitis at slit-lamp examination. A second patient had posterior subcapsular cataract associated with corticosteroid treatment. No signs of intraocular complications from previous unrecognized uveitis were observed in any patient. Conclusions: Children with IBD may have asymptomatic uveitis, yet its prevalence seems lower than previously reported, and it was not found in children without a previous diagnosis of clinically manifest uveitis. No ocular complications from prior unrecognized uveitis were observed.
KW - children
KW - extraintestinal manifestations
KW - inflammatory bowel disease
KW - uveitis
UR - http://www.scopus.com/inward/record.url?scp=85019735890&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85019735890&partnerID=8YFLogxK
U2 - 10.1097/MIB.0000000000001079
DO - 10.1097/MIB.0000000000001079
M3 - Review article
VL - 23
SP - 986
EP - 990
JO - Inflammatory Bowel Diseases
JF - Inflammatory Bowel Diseases
SN - 1078-0998
IS - 6
ER -